Gaynor Alexandra M, Chua Elizabeth F
a Department of Psychology , Brooklyn College of the City University of New York , Brooklyn , NY , USA.
b Department of Psychology , The Graduate Center of the City University of New York , New York , NY , USA.
Cogn Neurosci. 2017 Jul;8(3):156-161. doi: 10.1080/17588928.2016.1213713. Epub 2016 Aug 1.
Previous research has implicated the prefrontal cortex (PFC) in successful associative encoding and subjective awareness of one's memory performance. We tested the causal role of the PFC in these processes by applying transcranial direct current stimulation (tDCS) during a verbal associative encoding and judgment-of-learning (JOL) task. tDCS over the PFC impaired associative encoding compared to sham and parietal tDCS, as shown by fewer hits on a subsequent associative recognition test. There were no effects of tDCS on the magnitude or accuracy of JOLs. These results suggest the PFC plays a causal role in objective measures of encoding, and that objective and subjective aspects of associative encoding are separable.
先前的研究表明前额叶皮层（PFC）在成功的联想编码以及对自身记忆表现的主观意识中发挥作用。我们通过在言语联想编码和学习判断（JOL）任务期间应用经颅直流电刺激（tDCS）来测试PFC在这些过程中的因果作用。与假刺激和顶叶tDCS相比，PFC上的tDCS损害了联想编码，这在随后的联想识别测试中命中次数较少得到体现。tDCS对JOLs的大小或准确性没有影响。这些结果表明PFC在编码的客观测量中起因果作用，并且联想编码的客观和主观方面是可分离的。
