一例由单纯疱疹病毒1型感染引起的急性横贯性脊髓炎罕见病例。

An unusual case of acute transverse myelitis caused by HSV-1 infection.

作者信息

Figueroa Danisha, Isache Carmen, Sands Michael, Guzman Nilmarie

机构信息

Department of Internal Medicine, Division of Infectious Disease, University of Florida, College of Medicine-Jacksonville, United States.

出版信息

IDCases. 2016 Jun 22;5:29-31. doi: 10.1016/j.idcr.2016.05.007. eCollection 2016.

DOI:10.1016/j.idcr.2016.05.007

PMID:27419072

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4941118/

Abstract

Transverse myelitis is a neurological disorder of the spinal cord that can have a variety of etiologies. Herpes simplex virus (HSV) infection has been described as one of the causes, most commonly HSV type 2. We report here a case of an 18 year old male who presented with weakness that started in his upper extremities and rapidly evolved to quadriplegia. Magnetic resonance imaging of spine was consistent with transverse myelitis. HSV type 1 PCR testing on cerebrospinal fluid (CSF) was positive. He was started on acyclovir and steroids, but despite therapy, patient did not recover motor function.

摘要

横贯性脊髓炎是一种脊髓神经障碍性疾病，病因多样。单纯疱疹病毒（HSV）感染被认为是病因之一，最常见的是2型单纯疱疹病毒。我们在此报告一例18岁男性病例，该患者最初表现为上肢无力，随后迅速发展为四肢瘫痪。脊柱磁共振成像结果符合横贯性脊髓炎。脑脊液（CSF）的1型单纯疱疹病毒聚合酶链反应（PCR）检测呈阳性。患者开始接受阿昔洛韦和类固醇治疗，但尽管进行了治疗，患者的运动功能仍未恢复。