Adjiman S, Zerbib M, Flam T, Brochard M, Deslignères S, Boissonnas A, Debré B, Steg A
Clinique Urologique, Hôpital Cochin, Paris.
Ann Urol (Paris). 1989;23(3):179-81.
Four patients with solid genito-urinary tumors and HIV 1 infection have been treated in our institution over the last 2 years, including 2 with seminoma, 1 with renal adenocarcinoma and 1 with renal angiosarcoma. All had severely impaired immunity with a low CD4 level. Three had or developed a true AIDS syndrome according to the WHO and CDC criteria (1988). The remaining patient was seropositive and died less than 3 months following the diagnosis of renal angiosarcoma, he is the first reported case of renal sarcoma in a patient infected with HIV 1. Two patients were homosexuals and the other 2 were drug addicts. Along with other reported cases, our cases may underline the association between depression of immunity due to HIV and onset of solid genito-urinary tumors.
在过去两年中，我们机构共治疗了4例患有实体性泌尿生殖系统肿瘤且感染了HIV 1的患者，其中2例为精原细胞瘤，1例为肾腺癌，1例为肾血管肉瘤。所有患者的免疫力均严重受损，CD4水平较低。根据世界卫生组织和美国疾病控制与预防中心（1988年）的标准，3例患者患有或发展为真正的艾滋病综合征。其余1例患者血清学呈阳性，在诊断为肾血管肉瘤后不到3个月死亡，他是首例报告的感染HIV 1的肾肉瘤患者。2例患者为同性恋者，另外2例为吸毒者。与其他报告的病例一起，我们的病例可能突显了HIV导致的免疫抑制与实体性泌尿生殖系统肿瘤发病之间的关联。
