Adjiman S, Zerbib M, Flam T, Brochard M, Deslignères S, Boissonnas A, Debré B, Steg A
Clinique Urologique, Hôpital Cochin, Paris, France.
Eur Urol. 1990;18(1):61-3. doi: 10.1159/000463869.
4 patients with solid genitourinary tumors and HIV1 infection have been treated in our institution over the last 2 years. Two patients had seminoma, 1 renal adenocarcinoma and 1 renal angiosarcoma. All had deeply impaired immunity with a low CD4 level. 3 had or developed a true AIDS syndrome according to the WHO and CDC criterias of 1988. The remaining patient was seropositive and died less than 3 months following the diagnosis of renal angiosarcoma. He is the first reported case of renal sarcoma in a patient infected with HIV1. 2 patients were homosexuals, and the 2 others were drug addicts. Along with other reported cases, our cases underline the association between the depression of immunity due to HIV and the onset of solid genitourinary tumors.
在过去两年中，我们机构对4例患有实体性泌尿生殖系统肿瘤且感染HIV1的患者进行了治疗。其中2例为精原细胞瘤，1例为肾腺癌，1例为肾血管肉瘤。所有患者的免疫力均严重受损，CD4水平较低。根据1988年世界卫生组织和美国疾病控制与预防中心的标准，3例患者患有或发展为真正的艾滋病综合征。其余1例患者血清学呈阳性，在诊断为肾血管肉瘤后不到3个月死亡。他是首例报告的感染HIV1患者发生肾肉瘤的病例。2例患者为同性恋者，另外2例为吸毒者。与其他报告的病例一样，我们的病例强调了HIV导致的免疫抑制与实体性泌尿生殖系统肿瘤发病之间的关联。
