Parkinsonism and amiodarone therapy.

We report a case of reversible, dose-related parkinsonian tremor in a patient taking amiodarone. In previous writings by others, basal ganglia dysfunction associated with amiodarone was dose related and reversibility was inversely related to duration of therapy. Patients receiving amiodarone are at risk for the development of basal ganglia dysfunction which may persist if the drug is not discontinued or the dosage reduced.