Cutting Elizabeth, Banchero Meghan, Beitelshees Amber L, Cimino James J, Fiol Guilherme Del, Gurses Ayse P, Hoffman Mark A, Jeng Linda Jo Bone, Kawamoto Kensaku, Kelemen Mark, Pincus Harold Alan, Shuldiner Alan R, Williams Marc S, Pollin Toni I, Overby Casey Lynnette
Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, United States.
Informatics Institute, School of Medicine, University of Alabama at Birmingham, Birmingham, AL, United States.
J Biomed Inform. 2016 Oct;63:1-10. doi: 10.1016/j.jbi.2016.07.014. Epub 2016 Jul 14.
The objective of this study was to develop a high-fidelity prototype for delivering multi-gene sequencing panel (GS) reports to clinicians that simulates the user experience of a final application. The delivery and use of GS reports can occur within complex and high-paced healthcare environments. We employ a user-centered software design approach in a focus group setting in order to facilitate gathering rich contextual information from a diverse group of stakeholders potentially impacted by the delivery of GS reports relevant to two precision medicine programs at the University of Maryland Medical Center. Responses from focus group sessions were transcribed, coded and analyzed by two team members. Notification mechanisms and information resources preferred by participants from our first phase of focus groups were incorporated into scenarios and the design of a software prototype for delivering GS reports. The goal of our second phase of focus group, to gain input on the prototype software design, was accomplished through conducting task walkthroughs with GS reporting scenarios. Preferences for notification, content and consultation from genetics specialists appeared to depend upon familiarity with scenarios for ordering and delivering GS reports. Despite familiarity with some aspects of the scenarios we proposed, many of our participants agreed that they would likely seek consultation from a genetics specialist after viewing the test reports. In addition, participants offered design and content recommendations. Findings illustrated a need to support customized notification approaches, user-specific information, and access to genetics specialists with GS reports. These design principles can be incorporated into software applications that deliver GS reports. Our user-centered approach to conduct this assessment and the specific input we received from clinicians may also be relevant to others working on similar projects.
本研究的目的是开发一个高保真原型，用于向临床医生提供多基因测序 panel（GS）报告，该原型模拟最终应用程序的用户体验。GS 报告的交付和使用可能发生在复杂且节奏快的医疗环境中。我们在焦点小组环境中采用以用户为中心的软件设计方法，以便从可能受到与马里兰大学医学中心两个精准医学项目相关的 GS 报告交付影响的不同利益相关者群体中收集丰富的背景信息。焦点小组会议的回复由两名团队成员进行转录、编码和分析。我们将第一阶段焦点小组参与者偏好的通知机制和信息资源纳入场景以及用于交付 GS 报告的软件原型设计中。我们第二阶段焦点小组的目标是获得对原型软件设计的意见，这一目标通过对 GS 报告场景进行任务演练来实现。遗传学专家对通知、内容和咨询的偏好似乎取决于对订购和交付 GS 报告场景的熟悉程度。尽管对我们提出的某些场景方面有所熟悉，但我们的许多参与者一致认为，他们在查看测试报告后可能会寻求遗传学专家的咨询。此外，参与者还提供了设计和内容方面的建议。研究结果表明，需要支持定制化通知方法、用户特定信息以及通过 GS 报告获取遗传学专家的服务。这些设计原则可纳入提供 GS 报告的软件应用程序中。我们以用户为中心进行此评估的方法以及从临床医生那里获得的具体意见，可能对从事类似项目的其他人也有参考价值。
