Blaser Susan I, Steinlin Maja, Al-Maawali Almundher, Yoon Grace
Division of Paediatric Neuroradiology, The Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Division of Neuropaediatrics, Development and Rehabilitation, University Children's Hospital Inselspital, University of Bern, Freiburgstrasse 4, Bern 3010, Switzerland.
Neuroimaging Clin N Am. 2016 Aug;26(3):373-416. doi: 10.1016/j.nic.2016.03.007.
Evaluation of imaging studies of the cerebellum in inherited neurodegenerative disorders is aided by attention to neuroimaging patterns based on anatomic determinants, including biometric analysis, hyperintense signal of structures, including the cerebellar cortex, white matter, dentate nuclei, brainstem tracts, and nuclei, the presence of cysts, brain iron, or calcifications, change over time, the use of diffusion-weighted/diffusion tensor imaging and T2*-weighted sequences, magnetic resonance spectroscopy; and, in rare occurrences, the administration of contrast material.
在遗传性神经退行性疾病中,对小脑成像研究的评估可通过关注基于解剖学决定因素的神经影像学模式来辅助,这些因素包括生物测量分析、小脑皮质、白质、齿状核、脑干束和核等结构的高信号、囊肿、脑铁或钙化的存在、随时间的变化、扩散加权/扩散张量成像和T2*加权序列的使用、磁共振波谱;以及在罕见情况下使用对比剂。