Sun Sue Yazaki, Goldstein Donald P, Bernstein Marilyn R, Horowitz Neil S, Mattar Rosiane, Maestá Izildinha, Braga Antonio, Berkowitz Ross S
J Reprod Med. 2016 May-Jun;61(5-6):210-4.
To investigate the frequency of potentially life-threatening conditions (PLTCs) and maternal near misses (MNMs) at the New England Trophoblastic Disease Center (NETDC) in recent years, when there has been earlier diagnosis of molar pregnancy.
This study included patients with molar pregnancy at the NETDC between 1994 and 2013. Clinical and pathologic reports were reviewed. PLTC and MNM criteria and maternal deaths were searched in medical records using the World Health Organization criteria and classification.
We identified 375 patients with molar pregnancy and no patient developed a MNM or maternal death. Only 6 (1.6%) had PLTCs (hemorrhage with hemodynamic instability, severe preeclampsia, respiratory distress, blood transfusion, and ICU admission).
We observed a low rate of PLTC and no cases of MNMs or maternal deaths related to molar pregnancy, likely due to earlier diagnosis at the NETDC in recent years.
调查近年来新英格兰滋养细胞疾病中心（NETDC）潜在危及生命情况（PLTCs）及孕产妇险些死亡（MNMs）的发生频率，近年来该中心对葡萄胎妊娠的诊断更为早期。
本研究纳入了1994年至2013年间在NETDC诊断为葡萄胎妊娠的患者。回顾了临床和病理报告。使用世界卫生组织的标准和分类在病历中查找PLTC和MNM标准以及孕产妇死亡情况。
我们确定了375例葡萄胎妊娠患者，无患者发生MNM或孕产妇死亡。仅有6例（1.6%）出现PLTCs（伴有血流动力学不稳定的出血、重度子痫前期、呼吸窘迫、输血及入住重症监护病房）。
我们观察到PLTC发生率较低，且无与葡萄胎妊娠相关的MNM或孕产妇死亡病例，这可能归因于近年来NETDC对葡萄胎妊娠的早期诊断。
