Iwuh I A, Fawcus S, Schoeman L
Princess Marina Hospital and University of Botswana, Gaborone, Botswana; Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of Cape Town, South Africa.
S Afr Med J. 2018 Feb 27;108(3):171-175. doi: 10.7196/SAMJ.2018.v108i3.12876.
A maternal near-miss is defined as a life-threatening pregnancy-related complication where the woman survives. The World Health Organization (WHO) has produced a tool for identifying near-misses according to criteria that include the occurrence of a severe maternal complication together with organ dysfunction and/or specified critical interventions. Maternal deaths have been audited in the public sector Metro West maternity service in Cape Town, South Africa, for many years, but there has been no monitoring of near-misses.
To measure the near-miss ratio (NMR), maternal mortality ratio (MMR) and mortality index (MI), and to investigate the near-miss cases.
A retrospective observational study conducted during 6 months in 2014 identified and analysed all near-miss cases and maternal deaths in Metro West, using the WHO criteria.
From a total of 19 222 live births, 112 near-misses and 13 maternal deaths were identified. The MMR was 67.6 per 100 000 live births and the NMR 5.83 per 1 000 live births. The maternal near-miss/maternal death ratio was 8.6:1 and the MI 10.4%. The major causes of near-miss were hypertension (n=50, 44.6%), haemorrhage (n=38, 33.9%) and puerperal sepsis (n=13, 11.6%). The first two conditions both had very low MIs (1.9% and 0%, respectively), whereas the figure for puerperal sepsis was 18.9%. Less common near-miss causes were medical/surgical conditions (n=7, 6.3%), non-pregnancy-related infections (n=2, 1.8%) and acute collapse (n=2, 1.8%), with higher MIs (33.3%, 66.7% and 33.3%, respectively). Critical interventions included massive blood transfusion (34.8%), ventilation (40.2%) and hysterectomy (30.4%). Considering health system factors, 63 near-misses (56.3%) initially occurred at a primary care facility, and the patients were all referred to the tertiary hospital; 38 (33.9%) occurred at a secondary hospital, and 11 (9.8%) at the tertiary hospital. Analysis of avoidable factors identified lack of antenatal clinic attendance (11.6%), inter-facility transport problems (6.3%) and health provider-related factors (25.9% at the primary level of care, 38.2% at secondary level and 7.1% at tertiary level).
The NMR and MMR for Metro West were lower than in other developing countries, but higher than in high-income countries. The MI was low for direct obstetric conditions (hypertension, haemorrhage and puerperal sepsis), reflecting good quality of care and referral mechanisms for these conditions. The MIs for non-pregnancy-related infections, medical/surgical conditions and acute collapse were higher, suggesting that medical problems need more focused attention.
孕产妇险些死亡被定义为与妊娠相关的危及生命的并发症,而该孕妇最终存活。世界卫生组织(WHO)制定了一种工具,用于根据包括严重孕产妇并发症的发生以及器官功能障碍和/或特定关键干预措施在内的标准来识别险些死亡情况。多年来,南非开普敦的公共部门西地铁地区产科服务一直在对孕产妇死亡情况进行审核,但尚未对险些死亡情况进行监测。
测量险些死亡率(NMR)、孕产妇死亡率(MMR)和死亡指数(MI),并调查险些死亡病例。
2014年进行了一项为期6个月的回顾性观察研究,采用WHO标准识别并分析了西地铁地区所有险些死亡病例和孕产妇死亡情况。
在总共19222例活产中,识别出112例险些死亡病例和13例孕产妇死亡。MMR为每10万例活产67.6例,NMR为每1000例活产5.83例。孕产妇险些死亡/孕产妇死亡比例为8.6:1,MI为10.4%。险些死亡的主要原因是高血压(n = 50,44.6%)、出血(n = 38,33.9%)和产褥期败血症(n = 13,11.6%)。前两种情况的MI都非常低(分别为1.9%和0%),而产褥期败血症的MI为18.9%。不太常见的险些死亡原因是内科/外科疾病(n = 7,6.3%)、非妊娠相关感染(n = 2,1.8%)和急性衰竭(n = 2,1.8%),MI较高(分别为33.3%、66.7%和33.3%)。关键干预措施包括大量输血(34.8%)、通气(40.2%)和子宫切除术(30.4%)。考虑到卫生系统因素,63例险些死亡病例(56.3%)最初发生在基层医疗机构,患者均被转诊至三级医院;38例(33.9%)发生在二级医院,11例(9.8%)发生在三级医院。对可避免因素的分析发现,产前门诊就诊率低(11.6%)、机构间转运问题(6.3%)以及与医疗服务提供者相关的因素(基层医疗水平为25.9%,二级医疗水平为38.2%,三级医疗水平为7.1%)。
西地铁地区的NMR和MMR低于其他发展中国家,但高于高收入国家。直接产科情况(高血压、出血和产褥期败血症)的MI较低,反映出对这些情况的优质护理和转诊机制。非妊娠相关感染、内科/外科疾病和急性衰竭的MI较高,表明医疗问题需要更集中的关注。