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胶原蛋白基质隧道技术与结缔组织移植治疗牙周退缩的比较:一项随机临床试验

Tunnel Technique With Collagen Matrix Compared With Connective Tissue Graft for Treatment of Periodontal Recession: A Randomized Clinical Trial.

作者信息

Cieślik-Wegemund Marta, Wierucka-Młynarczyk Beata, Tanasiewicz Marta, Gilowski Łukasz

机构信息

Department of Periodontal and Oral Mucosa Diseases, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia, Katowice, Poland.

Department of Conservative Dentistry with Endodontics, School of Medicine with the Division of Dentistry in Zabrze, Medical University of Silesia.

出版信息

J Periodontol. 2016 Dec;87(12):1436-1443. doi: 10.1902/jop.2016.150676. Epub 2016 Jul 17.

DOI:10.1902/jop.2016.150676
PMID:27424564
Abstract

BACKGROUND

The aim of this study is to compare efficacy of the tunnel technique for root coverage using collagen matrix (CM) versus connective tissue graft (CTG) for treatment of multiple recessions of Miller Classes I and II over a short period of time.

METHODS

Twenty-eight patients were enrolled in the study. Patients in the control group were treated with the tunnel technique using CTGs, whereas patients in the test group were treated with the tunnel technique using xenogeneic CM. Clinical recordings were obtained at baseline and after 3 and 6 months. Percentages of average recession coverage (ARC) and complete recession coverage (CRC) were evaluated 3 and 6 months after surgery.

RESULTS

Significant decreases were recorded in both groups of recession parameters compared with baseline measurements. Mean recession depth (0.21 versus 0.39 mm) and recession area (0.31 versus 0.53 mm) after 6 months were significantly higher in the test group (P <0.05). Mean keratinized tissue width (KTW) increased at a similar rate in both groups (1.0 versus 0.8 mm for control and test groups, respectively). ARC after 6 months was 95% in the control group and 91% in the test group (P <0.05), and CRC was 71.4% (10/14) in the control group and 14.3% (2/14) in the test group (P <0.05).

CONCLUSION

Xenogeneic CM combined with tunnel technique leads to satisfactory ARC and increase in KTW similar to CTG, but yields lower unsatisfactory CRC.

摘要

背景

本研究旨在比较使用胶原基质(CM)的隧道技术与结缔组织移植(CTG)在短期内治疗米勒I类和II类多处牙龈退缩的疗效。

方法

28例患者纳入本研究。对照组患者采用使用CTG的隧道技术进行治疗,而试验组患者采用使用异种CM的隧道技术进行治疗。在基线以及3个月和6个月后进行临床记录。在术后3个月和6个月评估平均退缩覆盖百分比(ARC)和完全退缩覆盖百分比(CRC)。

结果

与基线测量值相比,两组退缩参数均有显著下降。试验组6个月后的平均退缩深度(0.21对0.39mm)和退缩面积(0.31对0.53mm)显著更高(P<0.05)。两组的平均角化组织宽度(KTW)以相似的速率增加(对照组和试验组分别为1.0对0.8mm)。对照组6个月后的ARC为95%,试验组为91%(P<0.05),对照组的CRC为71.4%(10/14),试验组为14.3%(2/14)(P<0.05)。

结论

异种CM联合隧道技术可产生与CTG相似的令人满意的ARC和KTW增加,但产生的不满意CRC较低。

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