Widman Erik, Maksuti Elira, Amador Carolina, Urban Matthew W, Caidahl Kenneth, Larsson Matilda
Department of Medical Engineering, School of Technology and Health, KTH Royal Institute of Technology, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
Department of Medical Engineering, School of Technology and Health, KTH Royal Institute of Technology, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.
Ultrasound Med Biol. 2016 Oct;42(10):2423-35. doi: 10.1016/j.ultrasmedbio.2016.05.021. Epub 2016 Jul 15.
Five small porcine aortas were used as a human carotid artery model, and their stiffness was estimated using shear wave elastography (SWE) in the arterial wall and a stiffened artery region mimicking a stiff plaque. To optimize the SWE settings, shear wave bandwidth was measured with respect to acoustic radiation force push length and number of compounded angles used for motion detection with plane wave imaging. The mean arterial wall and simulated plaque shear moduli varied from 41 ± 5 to 97 ± 10 kPa and from 86 ± 13 to 174 ± 35 kPa, respectively, over the pressure range 20-120 mmHg. The results revealed that a minimum bandwidth of approximately 1500 Hz is necessary for consistent shear modulus estimates, and a high pulse repetition frequency using no image compounding is more important than a lower pulse repetition frequency with better image quality when estimating arterial wall and plaque stiffness using SWE.
使用五个小型猪主动脉作为人体颈动脉模型，通过剪切波弹性成像（SWE）对动脉壁和模拟硬斑块的硬化动脉区域的硬度进行估计。为了优化SWE设置，针对声辐射力推动长度和用于平面波成像运动检测的复合角度数量测量了剪切波带宽。在20 - 120 mmHg的压力范围内，动脉壁和模拟斑块的平均剪切模量分别在41±5至97±10 kPa和86±13至174±35 kPa之间变化。结果表明，对于一致的剪切模量估计，大约1500 Hz的最小带宽是必要的，并且在使用SWE估计动脉壁和斑块硬度时，不进行图像复合的高脉冲重复频率比具有更好图像质量的低脉冲重复频率更重要。
