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[匈牙利口腔癌筛查的成本效益]

[Cost-effectiveness of oral cancer screening in Hungary].

作者信息

Vokó Zoltán, Túri Gergő, Zsólyom Adriána

机构信息

Egészségpolitika és Egészség-gazdaságtan Tanszék, Eötvös Loránd Tudományegyetem, Társadalomtudományi Kar Budapest, Pázmány Péter sétány 1/A, 1117.

Syreon Kutató Intézet Budapest.

出版信息

Orv Hetil. 2016 Jul;157(29):1161-70. doi: 10.1556/650.2016.30447.

Abstract

INTRODUCTION

The burden of oral cancer is high in Hungary.

AIM

To study the cost-effectiveness of potential oral cancer screening in Hungary.

METHOD

Three strategies were compared: no introduction of screening, organized yearly screening for 40-year-old males in general medical practise, and opportunistic screening of high risk 40-year-old males in primary care. Local estimates of health utilities and costs of each health state and of the screening programmes were identified. The main outcomes were total costs, quality adjusted life years, and incremental cost-effectiveness ratios.

RESULTS

Depending on the efficacy of the treatments of precancerous lesions and the participation rate, screening strategies are cost-effective over a 15-20 year time course. The opportunistic screening of high risk people is more cost-effective than the other strategies.

CONCLUSIONS

Opportunistic screening of high risk people would be cost-effective in Hungary. The uncertainty about the efficacy of the treatments of precancerous lesions requires more research to support evidence based health policy making. Orv. Hetil., 2016, 157(29), 1161-1170.

摘要

引言

匈牙利口腔癌负担沉重。

目的

研究匈牙利潜在口腔癌筛查的成本效益。

方法

比较了三种策略:不引入筛查、在普通医疗实践中对40岁男性进行年度组织筛查、以及在初级保健中对高危40岁男性进行机会性筛查。确定了每个健康状态以及筛查计划的健康效用和成本的本地估计值。主要结果是总成本、质量调整生命年和增量成本效益比。

结果

根据癌前病变治疗的疗效和参与率,筛查策略在15至20年的时间范围内具有成本效益。对高危人群进行机会性筛查比其他策略更具成本效益。

结论

在匈牙利,对高危人群进行机会性筛查具有成本效益。癌前病变治疗疗效的不确定性需要更多研究来支持基于证据的卫生政策制定。《匈牙利医学周报》,2016年,157(29),1161 - 1170。

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