肿瘤学家对双膦酸盐相关颌骨坏死的认知。
Oncologists awareness about bisphosphonate related osteonecrosis of the jaws.
作者信息
Senturk Mehmet Fatih, Cimen Emre, Tuzuner Oncul Aysegul Mine, Cambazoglu Mine
机构信息
Dentistry Faculty, Oral and Maxillofacial Surgery Department, Suleyman Demirel University, Isparta, Turkey.
Dentistry, Oral and Maxillofacial Surgery, Ugurel Dental Clinic, Istanbul, Turkey.
出版信息
J Pak Med Assoc. 2016 Jul;66(7):880-3.
OBJECTIVE
To evaluate the oncologists thoughts about the positive and adverse effects of bisphosphonates, drug holiday and the awareness about BRONJ.
METHODS
A written questionnaire was sent to 7 hospitals, which have oncology facilities in Ankara, Turkey. Results were evaluated as percentages. Chi Square and Kruskal Wallis H test was used to analyze the data.
RESULTS
A total of 53 oncologists replied to the questionnaire. BRONJ is the most seen complication (66%) due to bisphosphonates usage. Temporary suspension of the drug (52.8%) is the best treatment choice for this complication. Oncologists usually prefered dentist consultatation (39.6%).
CONCLUSIONS
A good cooperation of oncologists and dentists is very important to prevent BRONJ.
目的
评估肿瘤学家对双膦酸盐的积极和不良影响、药物假期以及颌骨坏死性骨髓炎（BRONJ）的认识。
方法
向土耳其安卡拉设有肿瘤治疗设施的7家医院发送了一份书面调查问卷。结果以百分比进行评估。采用卡方检验和克鲁斯卡尔 - 沃利斯H检验来分析数据。
结果
共有53名肿瘤学家回复了问卷。BRONJ是双膦酸盐使用最常见的并发症（66%）。药物暂时停用（52.8%）是该并发症的最佳治疗选择。肿瘤学家通常倾向于咨询牙医（39.6%）。
结论
肿瘤学家和牙医的良好合作对于预防BRONJ非常重要。
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