Internal Medicine Department, Hospital San Pedro, Logroño, Spain.
Eur J Heart Fail. 2017 Jan;19(1):111-115. doi: 10.1002/ejhf.610. Epub 2016 Jul 18.
We have often found that patients with heart failure had shortness of breath when bending forward. The frequency of bendopnea in patients with decompensated heart failure (DHF), its repercussions on quality of life (QoL), and its prognosis have not yet been studied. This study was carried out to evaluate the characteristics, degree of limitation, and short-term prognosis of patients with bendopnea and DHF.
We conducted a study of 250 patients admitted with DHF. Bendopnea was considered when shortness of breath occurred within 30 s of bending forward. It was present in 122 patients (48.8%). The mean time of onset was 13.4 ± 6.9 s. Patients with bendopnea presented a higher frequency of orthopnoea, paroxysmal nocturnal dyspnoea, oliguria, oedema, elevated jugular venous pressure, abdominal fullness, and worse functional class (P < 0.001). An enlargement of both atria was more frequent in these patients (P < 0.001). Pulmonary artery systolic pressure (PASP) was higher in the bendopnea group (P = 0.001). Body mass index and LVEF were not associated with presence of bendopnea. Subjective QoL limitation was present in 80.3% (36.1% mild, 44.2% moderate to severe limitation). Patients with bendopnea had a higher mortality rate (P = 0.025) and more advanced NYHA class (P < 0.001). Patients who died had a lower LVEF (P = 0.001), increased PASP (P = 0.08), and lower mean duration of shortness of breath than those who survived (P = 0.01).
Bendopnea is related to advanced HF symptoms and it is associated with mortality in the short term and advanced NYHA functional class. This symptom produces moderate to severe limitation of QoL.
我们经常发现心力衰竭患者在向前弯腰时会出现呼吸急促。失代偿性心力衰竭(DHF)患者弯腰呼吸困难的频率、对生活质量(QoL)的影响及其预后尚未得到研究。本研究旨在评估弯腰呼吸困难和 DHF 患者的特征、受限程度和短期预后。
我们对 250 例因 DHF 入院的患者进行了一项研究。当患者向前弯腰 30 秒内出现呼吸困难时,认为存在弯腰呼吸困难。122 例患者(48.8%)存在弯腰呼吸困难。发病的平均时间为 13.4±6.9 秒。有弯腰呼吸困难的患者更频繁地出现端坐呼吸、阵发性夜间呼吸困难、少尿、水肿、颈静脉压升高、腹部饱胀和更差的功能分级(P<0.001)。这些患者的左右心房均增大更常见(P<0.001)。在弯腰呼吸困难组中,肺动脉收缩压(PASP)更高(P=0.001)。体质指数和左心室射血分数(LVEF)与弯腰呼吸困难的存在无关。主观 QoL 受限发生率为 80.3%(轻度 36.1%,中度至重度 44.2%)。有弯腰呼吸困难的患者死亡率更高(P=0.025),纽约心脏协会(NYHA)功能分级更高(P<0.001)。死亡患者的 LVEF 更低(P=0.001)、PASP 更高(P=0.08)、呼吸困难持续时间更短,而存活患者的 LVEF 更高(P=0.01)。
弯腰呼吸困难与晚期 HF 症状有关,与短期死亡率和晚期 NYHA 功能分级相关。该症状导致 QoL 出现中重度受限。