Zaruba A Iu, Kutsenko A I, Bosykh E G, Kukharchuk V V
Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1989;12(1):72-7.
Combination of isolated blood ultrafiltration (IBUF) and hemosorption (HS) produced subcompensation of severe congestive heart failure (CHF) in 10 of 14 patients refractory of IBUF alone and to drug therapy. HS included in the therapy complex was the only way to correct secondary hyperaldosteronism, to reduce antidiuretic hormone blood level, to increase diuresis and natriuresis and to reduce kaliuresis as well as to normalize blood electrolyte level. The withdrawal of excessive water with IBUF and bilirubin and creatinine with HS as well as direct detoxication effect on the liver with HS reduced in most patients hyperbilirubinemia, hypoproteinemia and azotemia--aggravating factors in patients with CHF.
单独血液超滤（IBUF）与血液吸附（HS）联合应用，使14例对单独IBUF及药物治疗无效的严重充血性心力衰竭（CHF）患者中的10例病情得到部分代偿。治疗方案中包含的HS是纠正继发性醛固酮增多症、降低抗利尿激素血水平、增加利尿和利钠作用以及减少尿钾排泄并使血电解质水平正常化的唯一方法。通过IBUF排出过多水分，通过HS清除胆红素和肌酐，以及HS对肝脏的直接解毒作用，使大多数CHF患者的高胆红素血症、低蛋白血症和氮质血症（CHF患者的加重因素）得以减轻。
