Zaruba A Iu, Kutsenko A I, Kukharchuk V V, Mal'ginov S V, Masenko V P
Ter Arkh. 1989;61(4):84-7.
Application of isolated ultrafiltration (IUF) of blood in 70 out of 100 patients with refractory heart failure (HF) made it possible, acting on some mechanisms of water excretion disorders, to attain the compensation for the HF signs. At the same time the correction of the manifestations of secondary hyperaldosteronism, hypoproteinemia, hyperbilirubinemia, and azotemia was attained only thanks to the presence of the functional reserves of the liver and kidneys. In 35 patients with cachectic HF, IUF failure was determined by marked cardial liver cirrhosis together with depletion of the functional reserves of the cardiovascular system. The lack of sufficient diuresis, hyponatremia, hypoproteinemia, and hyperbilirubinemia may be unfavourable prognostic signs despite the reduction of HF intensity consequent on IUF.
对100例难治性心力衰竭(HF)患者中的70例应用血液单纯超滤(IUF),通过作用于水排泄障碍的某些机制,有可能实现心力衰竭体征的代偿。与此同时,仅由于肝脏和肾脏功能储备的存在,才实现了继发性醛固酮增多症、低蛋白血症、高胆红素血症和氮质血症表现的纠正。在35例恶病质型心力衰竭患者中,IUF失败是由明显的心源性肝硬化以及心血管系统功能储备耗竭所决定的。尽管IUF后心力衰竭强度有所降低,但利尿不足、低钠血症、低蛋白血症和高胆红素血症可能是不良的预后体征。