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[血小板聚集初始阶段的结构功能状态]

[Structural-functional state of platelets at the initial stage of aggregation].

作者信息

Samal' A B, Cherenkevich S N, Khmara N F

出版信息

Biofizika. 1989 Mar-Apr;34(2):267-71.

PMID:2742900
Abstract

ADP-induced changes of light transmission of platelet suspension were studied with a laser aggregometer at concentration variation of both cells and aggregation agents. It was shown that a decrease of light transmission of platelet suspension was due to structure-morphological changes of platelets and pseudopodia formation. An investigation method of platelet aggregation with a small content of cells in the solution permits to fix distinctly the stages of the platelet structural states in the processes of stimulation and aggregation.

摘要

采用激光聚集仪,在细胞和聚集剂浓度变化的情况下,研究了二磷酸腺苷(ADP)诱导的血小板悬液透光率变化。结果表明,血小板悬液透光率降低是由于血小板的结构形态变化和伪足形成。一种用于研究溶液中细胞含量少的血小板聚集的方法,能够清晰地确定刺激和聚集过程中血小板结构状态的各个阶段。

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