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手部恶性溃疡性肢端黑色素瘤的罕见病例报告

A Rare Disease Presentation of Malignant Fungating Acral Melanoma of the Hand.

作者信息

Anthony Taylor, Goodman Aubree, Fan Juston, Gnass Ronaldo D, Sherman Christopher L, Thomson Bryon

机构信息

Department of Orthopaedic Surgery, Riverside University Health System, Moreno Valley, CA.

Department of Pathology, Riverside University Health System, Moreno Valley, CA.

出版信息

J Hand Surg Glob Online. 2023 Feb 25;5(3):386-390. doi: 10.1016/j.jhsg.2023.01.015. eCollection 2023 May.

Abstract

Malignant melanoma is relatively uncommon and accounts for 1%-3% of all malignant tumors. Malignant melanoma of the hand is exceptionally rare and highly malignant, with rapid progression if left untreated. Early clinical symptoms can be overlooked, and the tumor is often at a late stage when patients seek care, prompting amputation of the affected region. We present a case of a 48-year-old man who presented with a rapidly progressive, large, fungating mass of the distal aspect of the little finger diagnosed as malignant melanoma. We describe the presentation and treatment of this patient, who ultimately underwent partial amputation of the fifth metacarpal. Histologic analysis demonstrated nodular melanoma.

摘要

恶性黑色素瘤相对少见,占所有恶性肿瘤的1%-3%。手部恶性黑色素瘤极为罕见且恶性程度高,若不治疗,病情进展迅速。早期临床症状可能被忽视,患者就医时肿瘤往往已处于晚期,常需对患部进行截肢。我们报告一例48岁男性患者,其小指远端出现一个快速进展的、巨大的、呈蕈状的肿块,诊断为恶性黑色素瘤。我们描述了该患者的临床表现及治疗过程,该患者最终接受了第五掌骨部分切除术。组织学分析显示为结节性黑色素瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea5a/10264841/cca9ba7a8140/gr1.jpg

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