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通过ANS指数量化的交感-迷走神经平衡可预测行下段剖宫产的产妇术后发生低血压及血管升压药的使用需求:一项单盲前瞻性观察性研究。

Sympatho-vagal balance, as quantified by ANSindex, predicts post spinal hypotension and vasopressor requirement in parturients undergoing lower segmental cesarean section: a single blinded prospective observational study.

作者信息

Prashanth Anitha, Chakravarthy Murali, George Antony, Mayur Rohini, Hosur Rajathadri, Pargaonkar Sumant

机构信息

Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.

出版信息

J Clin Monit Comput. 2017 Aug;31(4):805-811. doi: 10.1007/s10877-016-9906-9. Epub 2016 Jul 18.

DOI:10.1007/s10877-016-9906-9
PMID:27430490
Abstract

Hypotension subsequent to spinal anesthesia occurs in a significant number of parturients undergoing lower segment caesarian section. Currently available methods to predict the incidence of hypotension, its severity and the outcome are sub-optimal. Many workers have used basal heart rate as one of the predictors. But using this method it is not possible to objectively analyze and predict the extent and severity of hypotension. We used an equipment measuring the level of sympatho-vagal balance, ANSiscope™, which derives these values from computed value of RR interval variability. We made a single measure of the value which was blinded to the patient and the anesthesiologist. We studied one hundred eight patients who underwent lower segment caesarian section under spinal anesthesia and found the variability of preoperative ANSindex (% activity displayed by the equipment) from 9 to 65 %. Higher ANSindex value was significantly associated with post spinal hypotension (p 0.017). A value of 24 % indicated the critical level above which hypotension appeared commonly. The ANSindex value might help anesthesiologist to anticipate and prepare for hypotension that is likely to ensue.

摘要

脊髓麻醉后低血压在大量接受下段剖宫产的产妇中发生。目前可用的预测低血压发生率、严重程度及后果的方法并不理想。许多研究人员将基础心率作为预测指标之一。但使用这种方法无法客观地分析和预测低血压的程度和严重程度。我们使用了一种测量交感-迷走平衡水平的设备ANSiscope™,它从RR间期变异性的计算值中得出这些数值。我们对该值进行了一次测量,对患者和麻醉医生均隐瞒该测量结果。我们研究了108例在脊髓麻醉下接受下段剖宫产的患者,发现术前ANS指数(设备显示的%活性)的变异性为9%至65%。较高的ANS指数值与脊髓麻醉后低血压显著相关(p = 0.017)。24%的值表明了一个临界水平,高于此水平低血压通常会出现。ANS指数值可能有助于麻醉医生预测并为可能发生的低血压做好准备。

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