Biological Chemistry and Chemometrics, Institute of Chemistry, Federal University of Rio Grande of Norte, Natal 59072-970, RN-Brazil.
Analyst. 2016 Aug 2;141(16):4833-47. doi: 10.1039/c6an01247g.
This review focuses on chemometric techniques applied in MIR-biospectroscopy for cancer diagnosis and analysis over the last ten years of research. Experimental applications of chemometrics coupled with biospectroscopy are discussed throughout this work. The advantages and drawbacks of this association are also highlighted. Chemometric algorithms are evidenced as a powerful tool for cancer diagnosis, classification, and in different matrices. In fact, it is shown how chemometrics can be implemented along all different types of cancer analyses.
本综述重点介绍了过去十年中在 MIR 生物光谱学用于癌症诊断和分析方面应用的化学计量学技术。本文讨论了化学计量学与生物光谱学相结合的实验应用。还强调了这种组合的优点和缺点。化学计量算法被证明是癌症诊断、分类和不同基质分析的有力工具。事实上,本文展示了如何在各种类型的癌症分析中实施化学计量学。