Institute of Next Generation Matter Transformation, College of Chemical Engineering and College of Material Sciences Engineering at Huaqiao University , 668 Jimei Boulevard, Xiamen, Fujian 361021, P. R. China.
National Laboratory for Molecular Sciences, Institute of Chemistry, CAS , Beijing, 100190, P. R. China.
Org Lett. 2016 Aug 5;18(15):3702-5. doi: 10.1021/acs.orglett.6b01740. Epub 2016 Jul 19.
A novel domino palladium-catalyzed nitration of Meyer-Schuster intermediates which were generated in situ from propargylic alcohols was developed, by the use of t-BuONO, leading to α-nitro enones in good to excellent yields at room temperature with a broad functional group tolerance.
发展了一种新型的钯催化多米诺硝化反应，该反应利用 t-BuONO，由炔丙醇原位生成的 Meyer-Schuster 中间体，在室温下以良好到优秀的收率得到了α-硝基烯酮，具有广泛的官能团容忍性。
