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South Asian individuals with diabetes who are referred for MODY testing in the UK have a lower mutation pick-up rate than white European people.

作者信息

Misra Shivani, Shields Beverley, Colclough Kevin, Johnston Desmond G, Oliver Nick S, Ellard Sian, Hattersley Andrew T

机构信息

Diabetes, Endocrinology and Metabolism, Imperial College London, Ground Floor Medical School Building, St Mary's Campus, Norfolk Place, London, W2 1PG, UK.

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK.

出版信息

Diabetologia. 2016 Oct;59(10):2262-5. doi: 10.1007/s00125-016-4056-7. Epub 2016 Jul 19.

DOI:10.1007/s00125-016-4056-7
PMID:27435864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5016539/
Abstract
摘要

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本文引用的文献

1
Maturity onset diabetes of the young in India - a distinctive mutation pattern identified through targeted next-generation sequencing.印度青年发病型成年糖尿病——通过靶向二代测序确定的独特突变模式
Clin Endocrinol (Oxf). 2015 Apr;82(4):533-42. doi: 10.1111/cen.12541. Epub 2014 Aug 7.
2
The 0.1% of the population with glucokinase monogenic diabetes can be recognized by clinical characteristics in pregnancy: the Atlantic Diabetes in Pregnancy cohort.在妊娠期间，通过临床特征可以识别出患有葡萄糖激酶单基因糖尿病的人群，占总人口的 0.1%：大西洋妊娠糖尿病队列研究。
Diabetes Care. 2014;37(5):1230-6. doi: 10.2337/dc13-2248. Epub 2014 Feb 18.
3
Glucokinase gene mutations (MODY 2) in Asian Indians.亚洲印第安人葡萄糖激酶基因突变（MODY2）。
Diabetes Technol Ther. 2014 Mar;16(3):180-5. doi: 10.1089/dia.2013.0244. Epub 2014 Jan 9.
4
Prevalence, characteristics and clinical diagnosis of maturity onset diabetes of the young due to mutations in HNF1A, HNF4A, and glucokinase: results from the SEARCH for Diabetes in Youth.因 HNF1A、HNF4A 和葡萄糖激酶基因突变导致的青年起病成年型糖尿病的患病率、特征和临床诊断：来自 SEARCH for Diabetes in Youth 的结果。
J Clin Endocrinol Metab. 2013 Oct;98(10):4055-62. doi: 10.1210/jc.2013-1279. Epub 2013 Jun 14.
5
The development and validation of a clinical prediction model to determine the probability of MODY in patients with young-onset diabetes.开发和验证一种临床预测模型，以确定年轻起病糖尿病患者中 MODY 的可能性。
Diabetologia. 2012 May;55(5):1265-72. doi: 10.1007/s00125-011-2418-8. Epub 2012 Jan 5.
6
Comprehensive molecular analysis of Japanese patients with pediatric-onset MODY-type diabetes mellitus.对日本儿科起病的 MODY 型糖尿病患者进行全面的分子分析。
Pediatr Diabetes. 2012 Feb;13(1):26-32. doi: 10.1111/j.1399-5448.2011.00827.x. Epub 2011 Nov 8.
7
Asian MODY: are we missing an important diagnosis?亚洲成年发病型糖尿病：我们是否遗漏了一项重要诊断？
Diabet Med. 2006 Nov;23(11):1257-60. doi: 10.1111/j.1464-5491.2006.01958.x.
8
First UK survey of paediatric type 2 diabetes and MODY.英国首次对儿童2型糖尿病和青少年发病的成年型糖尿病的调查。
Arch Dis Child. 2004 Jun;89(6):526-9. doi: 10.1136/adc.2003.027821.