Mayrovitz Harvey N, Corbitt Kelly, Grammenos Alexandra, Abello Allen, Mammino Jason
College of Medical Sciences, Nova Southeastern University, Ft. Lauderdale, FL, USA.
College of Osteopathic Medicine, Nova Southeastern University, Ft. Lauderdale, FL, USA.
Skin Res Technol. 2017 Feb;23(1):112-120. doi: 10.1111/srt.12310. Epub 2016 Jul 20.
Our goal was to test the hypothesis that skin firmness correlates with skin hydration.
Dermal water was assessed by tissue dielectric constant (TDC) at 0.5 mm (TDC ) and 2.5 mm (TDC ) depths on four face sites and two arm sites of 35 women (25.0 ± 1.6 years). Firmness was determined by force (mN) to indent skin to 0.3 mm (F ) and 1.3 mm (F ).
F was similar among face sites (avg = 16.2 ± 7.2 mN) but F varied (avg = 32.5 ± 4.1 mN). TDC was similar among face sites (avg = 37.7 ± 4.2) but TDC varied (avg = 36.2 ± 4.8). F of arm sites was similar (avg = 60.2 ± 18.6 mN) and both greater than F of neck (28.3 ± 7.1 mN) and face. Regression analysis showed a near-zero correlation between forces and TDC at all sites.
The near-zero correlation may be due to low skin interstitial hydraulic resistance to mobile water movement in healthy young skin. If true, then conditions in which dermal hydraulic conductance is reduced as in lymphedematous, diabetic, or aged skin are more likely show the hypothesized relationship. Our findings provide normalized reference values and suggest that such persons are an important population to study to test for a possible skin water-indentation force relationship and its utilization for early diagnosis.
我们的目标是检验皮肤紧致度与皮肤水合作用相关的假设。
通过组织介电常数(TDC)在35名女性(25.0±1.6岁)的四个面部部位和两个手臂部位的0.5毫米(TDC )和2.5毫米(TDC )深度处评估真皮水分。通过将皮肤压痕至0.3毫米(F )和1.3毫米(F )的力(毫牛顿)来确定紧致度。
面部各部位的F相似(平均值 = 16.2±7.2毫牛顿),但F有所不同(平均值 = 32.5±4.1毫牛顿)。面部各部位的TDC相似(平均值 = 37.7±4.2),但TDC有所不同(平均值 = 36.2±4.8)。手臂部位的F相似(平均值 = 60.2±18.6毫牛顿),且均大于颈部(28.3±7.1毫牛顿)和面部的F。回归分析显示所有部位的力与TDC之间的相关性接近零。
相关性接近零可能是由于健康年轻皮肤中皮肤间质对流动水分运动的水力阻力较低。如果是这样,那么在淋巴水肿、糖尿病或老年皮肤中真皮水力传导率降低的情况下,更有可能显示出假设的关系。我们的研究结果提供了标准化的参考值,并表明这类人群是研究皮肤水-indentation力关系及其在早期诊断中的应用可能性的重要研究对象。