Seyyedi Fatemeh, Rafiean-Kopaei Mahmoud, Miraj Sepideh
Resident, Department of Obstetrics and Gynecology, Medical Plants Research Center, Shahrekord University of Medical Sciences , Shahrekord, Iran .
Professor, Department of Cellular and Molecular Researches, Medical Plants Research Center, Shahrekord University of Medical Sciences , Shahrekord, Iran .
J Clin Diagn Res. 2016 May;10(5):QC01-5. doi: 10.7860/JCDR/2016/17844.7715. Epub 2016 May 1.
Several causes can disturb the quality of life in postmenopausal women. Stress, urinary incontinence is one of the factors that can influence the quality of life of women, since they evade social activities and limit their behavior. Vulvovaginal disorders adversely impacts sexual action, psychosocial health, and partner relationships.
The aim of this study was to examine the therapeutic properties of vaginal cream of royal jelly and estrogen on quality of life, sexual and urinary problems in postmenopausal women.
This study was a randomized controlled clinical trial that was done on 90 married postmenopausal women 50 to 65-year-old. A total of 90 women were randomly distributed to three groups and were treated with vaginal cream of royal jelly 15%, lubricant, and conjugated estrogens for three months. Before and after intervention, quality of life and vaginal cytology were evaluated. Data was analysed by SPSS 16 using ANOVA and Tukey tests.
The results expressed that vaginal royal jelly is considerably more effective than conjugated estrogens and lubricant in the improvement of quality of life, sexual and urinary function in postmenopausal women (p<0.05). Results of Pap smear showed that improvement of vaginal atrophy in conjugated estrogens group was better than other groups (p<0.001), and there was no significant difference between lubricant and royal jelly groups (p=0.89).
The effectiveness of vaginal royal jelly in treatment of sexual and urinary problems of postmenopausal women is related to its estrogenic properties and could be suitable in promotion of life quality in postmenopausal women.
多种原因会影响绝经后女性的生活质量。压力性尿失禁是影响女性生活质量的因素之一,因为她们会回避社交活动并限制自身行为。外阴阴道疾病会对性行为、心理社会健康及伴侣关系产生不利影响。
本研究旨在探讨蜂王浆阴道乳膏与雌激素对绝经后女性生活质量、性问题及泌尿问题的治疗作用。
本研究为一项随机对照临床试验,对90名年龄在50至65岁的已婚绝经后女性进行。总共90名女性被随机分为三组,分别用15%的蜂王浆阴道乳膏、润滑剂和结合雌激素治疗三个月。在干预前后,对生活质量和阴道细胞学进行评估。使用SPSS 16软件通过方差分析和Tukey检验对数据进行分析。
结果表明,在改善绝经后女性的生活质量、性功能和泌尿功能方面,蜂王浆阴道乳膏比结合雌激素和润滑剂更有效(p<0.05)。巴氏涂片结果显示,结合雌激素组阴道萎缩的改善情况优于其他组(p<0.001),润滑剂组和蜂王浆组之间无显著差异(p=0.89)。
蜂王浆阴道乳膏治疗绝经后女性性问题和泌尿问题的有效性与其雌激素特性有关,可能适合提高绝经后女性的生活质量。