Akbaş Murat, Şen Cihat, Calay Zerrin
Department of Obstetrics and Gynecology, Okmeydani Research Hospital, 34382 Istanbul, Turkey.
Department of Obstetrics and Gynecology, Cerrahpasa Faculty of Medicine, Istanbul University, 34098 Istanbul, Turkey.
Int Sch Res Notices. 2014 Jul 13;2014:890534. doi: 10.1155/2014/890534. eCollection 2014.
Aim. To evaluate the relationship between uterine artery Doppler indices and placental bed histopathology independent of clinical outcome. Materials and Methods. Uterine artery measurements were performed to 510 pregnant women who had come for routine antenatal care in 11-14th and 20-24th weeks. Placental bed biopsies from 141 cases were taken during cesarean section. Physiological changes and abnormal placental histology findings were investigated and compared with Doppler findings. Results. 116 biopsies were accepted as adequate biopsy and included in the study. Physiological changes were seen in 100 biopsies. Statistically significant higher PI and RI values in second trimester and higher notch rate in both trimesters were detected in the abnormal placental histology group (P < 0,001). Conclusion. Strong relationship between uterine artery Doppler indices and preeclampsia or intrauterine growth retardation has been shown in previous studies. In our study, we concluded that there is significant relationship between Doppler findings and placental bed histopathology independent of clinical course.
目的。评估子宫动脉多普勒指数与胎盘床组织病理学之间的关系，而不考虑临床结局。材料与方法。对510名在孕11 - 14周和20 - 24周前来进行常规产前检查的孕妇进行子宫动脉测量。在剖宫产时从141例病例中获取胎盘床活检组织。研究生理变化和异常胎盘组织学发现，并与多普勒检查结果进行比较。结果。116份活检组织被认为是足够的活检样本并纳入研究。100份活检组织出现生理变化。在异常胎盘组织学组中，检测到孕中期的搏动指数（PI）和阻力指数（RI）值在统计学上显著更高，且两个孕期的切迹率均更高（P < 0.001）。结论。先前的研究表明子宫动脉多普勒指数与子痫前期或胎儿生长受限之间存在密切关系。在我们的研究中，我们得出结论，多普勒检查结果与胎盘床组织病理学之间存在显著关系，且与临床过程无关。
