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The L-type Ca channel: A mediator of hypertrophic cardiomyopathy.

作者信息

Viola Helena M, Hool Livia C

机构信息

a School of Anatomy, Physiology and Human Biology, The University of Western Australia , Crawley , WA , Australia.

b Victor Chang Cardiac Research Institute , Sydney , NSW , Australia.

出版信息

Channels (Austin). 2017 Jan 2;11(1):5-7. doi: 10.1080/19336950.2016.1213053. Epub 2016 Jul 20.

DOI:10.1080/19336950.2016.1213053
PMID:27437722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5279882/
Abstract
摘要

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本文引用的文献

1
The Role of the L-Type Ca Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy.L型钙通道在肥厚型心肌病小鼠模型代谢活动改变中的作用
JACC Basic Transl Sci. 2016 Feb 13;1(1-2):61-72. doi: 10.1016/j.jacbts.2015.12.001. eCollection 2016 Jan-Feb.
2
The L-type Ca(2+) channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy.在肥厚型心肌病的cTnI-G203S小鼠模型中，L型钙通道促进异常代谢活动。
J Physiol. 2016 Jul 15;594(14):4051-70. doi: 10.1113/JP271681. Epub 2016 Jun 12.
3
Impaired functional communication between the L-type calcium channel and mitochondria contributes to metabolic inhibition in the mdx heart.L 型钙通道与线粒体之间功能通讯障碍导致 mdx 心脏代谢抑制。
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):E2905-14. doi: 10.1073/pnas.1402544111. Epub 2014 Jun 26.
4
Evidence of altered guinea pig ventricular cardiomyocyte protein expression and growth in response to a 5 min in vitro exposure to H(2)O(2).过氧化氢对豚鼠心室肌细胞蛋白表达和生长的影响：体外 5 分钟暴露试验
J Proteome Res. 2010 Apr 5;9(4):1985-94. doi: 10.1021/pr9011393.
5
Evidence for regulation of mitochondrial function by the L-type Ca2+ channel in ventricular myocytes.心室肌细胞中L型钙通道对线粒体功能调控的证据。
J Mol Cell Cardiol. 2009 Jun;46(6):1016-26. doi: 10.1016/j.yjmcc.2008.12.015. Epub 2009 Jan 7.
6
Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration.微管蛋白结合可阻断线粒体电压依赖性阴离子通道并调节呼吸作用。
Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18746-51. doi: 10.1073/pnas.0806303105. Epub 2008 Nov 24.
7
Transient exposure to hydrogen peroxide causes an increase in mitochondria-derived superoxide as a result of sustained alteration in L-type Ca2+ channel function in the absence of apoptosis in ventricular myocytes.在心室肌细胞未发生凋亡的情况下，短暂暴露于过氧化氢会导致线粒体衍生的超氧化物增加，这是由于L型钙离子通道功能持续改变所致。
Circ Res. 2007 Apr 13;100(7):1036-44. doi: 10.1161/01.RES.0000263010.19273.48. Epub 2007 Mar 8.
8
Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy.来自家族性肥厚型心肌病新型心肌肌钙蛋白I小鼠模型的分子见解。
J Mol Cell Cardiol. 2006 Oct;41(4):623-32. doi: 10.1016/j.yjmcc.2006.07.016. Epub 2006 Sep 1.