Santos Carla Manfredi, Cassiani Rachel Aguiar, Dantas Roberto Oliveira
Fonoaudiologia, Centro de Reabilitação, Hospital do Estado, Ribeirão Preto, SP, Brasil.
Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brasil.
Arq Gastroenterol. 2016 Jul-Sep;53(3):136-40. doi: 10.1590/S0004-28032016000300003.
There are some studies in the literature about the feeding behavior and masticatory process in patients with feeding disorders; however, it is not very well known if there are alterations in oral-pharyngeal swallowing dynamics in subjects with anorexia nervosa.
To evaluate the oral and pharyngeal bolus transit in patients with anorexia nervosa.
The study was conducted with 8 individuals clinically diagnosed and in treatment for restricting-type anorexia nervosa (seven women and one man), and 14 healthy individuals with no digestive or neurological symptoms (10 women, 4 men). Swallows were evaluated by videofluoroscopy with three swallows of 5 mL liquid bolus and three swallows of 5 mL paste bolus consistency, given in a random sequence. The participants were asked after each swallow about the sensation of the bolus passage.
In the analysis of oral-pharyngeal transit duration, the mean duration of pharyngeal transit with paste bolus in patients with anorexia was shorter than in healthy volunteers (P=0.02). In the duration of movement of the hyoid bone, longer movement was observed in anorexia than in healthy volunteers with liquid bolus (P=0.01). With liquid bolus, five (62.5%) patients and one (7.1%) control had sensation of the bolus passage (P<0.05).
There seems to be no important alterations of swallowing in subjects with anorexia nervosa, although the results suggest that pharyngeal transit has shorter duration than that seen in healthy volunteers and the hyoid movement duration is longer in patients than in healthy volunteers. Fast pharyngeal transit may be the cause of bolus transit perception in patients with anorexia nervosa.
文献中有一些关于进食障碍患者进食行为和咀嚼过程的研究；然而，神经性厌食症患者的口咽吞咽动力学是否存在改变尚不太清楚。
评估神经性厌食症患者的口腔和咽部食团通过情况。
该研究纳入了8例临床诊断为限制型神经性厌食症并正在接受治疗的个体（7名女性和1名男性），以及14名无消化或神经症状的健康个体（10名女性，4名男性）。通过电视荧光吞咽造影术进行评估，随机顺序给予3次5 mL液体食团吞咽和3次5 mL糊状食团吞咽。每次吞咽后询问参与者关于食团通过的感觉。
在口咽通过时间分析中，神经性厌食症患者糊状食团的咽部通过平均时间短于健康志愿者（P = 0.02）。在舌骨运动时间方面，神经性厌食症患者液体食团的运动时间长于健康志愿者（P = 0.01）。对于液体食团而言，5名（62.5%）患者和1名（7.1%）对照有食团通过的感觉（P < 0.05）。
神经性厌食症患者的吞咽似乎没有重要改变，尽管结果表明其咽部通过时间比健康志愿者短，且患者的舌骨运动时间比健康志愿者长。快速的咽部通过可能是神经性厌食症患者食团通过感觉的原因。
