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盐的科学:2014年6月至2015年5月高质量临床盐结局研究的系统评价

The Science of Salt: A Systematic Review of Quality Clinical Salt Outcome Studies June 2014 to May 2015.

作者信息

Johnson Claire, Raj Thout Sudhir, Trieu Kathy, Arcand JoAnne, Wong Michelle M Y, McLean Rachael, Leung Alexander, Campbell Norm R C, Webster Jacqui

机构信息

George Institute for Global Health, University of Sydney, Sydney, NSW, Australia.

Research & Development, the George Institute for Global Health, Hyderabad, India.

出版信息

J Clin Hypertens (Greenwich). 2016 Sep;18(9):832-9. doi: 10.1111/jch.12877. Epub 2016 Jul 21.

Abstract

Studies identified from an updated systematic review (from June 2014 to May 2015) on the impact of dietary salt intake on clinical and population health are reviewed. Randomized controlled trials, cohort studies, and meta-analyses of these study types on the effect of sodium intake on blood pressure, or any substantive adverse health outcomes were identified from MEDLINE searches and quality indicators were used to select studies that were relevant to clinical and public health. From 6920 studies identified in the literature search, 144 studies were selected for review, of which only three (n=233,680) met inclusion criteria. Between them, the three studies demonstrated a harmful association between excess dietary salt and all-cause mortality, noncardiovascular and cardiovascular disease mortality, and headache. None of the included studies found harm from lowering dietary salt. The findings of this systematic review are consistent with the large body of research supportive of efforts to reduce population salt intake and congruent with our last annual review from June 2013 to May 2014.

摘要

对从一项关于饮食盐摄入量对临床和人群健康影响的最新系统评价(2014年6月至2015年5月)中识别出的研究进行了综述。通过医学文献数据库检索,识别出关于钠摄入量对血压影响或任何实质性不良健康结局的随机对照试验、队列研究以及这些研究类型的荟萃分析,并使用质量指标来选择与临床和公共卫生相关的研究。在文献检索中识别出的6920项研究中,选取了144项研究进行综述,其中只有三项(n = 233,680)符合纳入标准。这三项研究共同表明,过量饮食盐与全因死亡率、非心血管和心血管疾病死亡率以及头痛之间存在有害关联。纳入的研究均未发现降低饮食盐有危害。该系统评价的结果与大量支持降低人群盐摄入量努力的研究一致,并且与我们上一次2013年6月至2014年5月的年度综述一致。

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