[Effect of dopamine on the blood circulation and metabolism in the brain during ischemia].
作者信息
Pchelintseva T R, Pogorelyĭ V E, Gaevyĭ M D
出版信息
Farmakol Toksikol. 1989 Mar-Apr;52(2):37-40.
PMID:2744141
Abstract
In acute experiments on anesthetized cats under blood autoperfusion of cerebral and peripheral vessels with a stable volume of blood during cerebral ischemia there was revealed the vascular and metabolic effects of dopamine on cerebral circulation. Administration of dopamine by perfusion in a dose of 100 micrograms/kg/min for 35 min after ischemia inhibited the development of postischemic hypoperfusion of the brain and also eliminated postischemic hypotension. A significant effect of dopamine on oxidative metabolism of the brain was observed.
摘要
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