Kovalev I E, Riabinina N E
Farmakol Toksikol. 1989 Mar-Apr;52(2):53-5.
Gamma-aminobutyric acid (GABA) was shown to exert the immunodepressive effect. The use of GABA under induction of cytochrome P-450 of the liver by phenobarbital or rifampicin was not followed by immunodepression. The obtained data indicate the dependence of GABA pharmacological activity from the function of cytochrome P-450-dependent monooxygenase system of the liver.
γ-氨基丁酸（GABA）已被证明具有免疫抑制作用。在苯巴比妥或利福平诱导肝脏细胞色素P-450的情况下使用GABA，并未出现免疫抑制现象。所获得的数据表明，GABA的药理活性依赖于肝脏细胞色素P-450依赖性单加氧酶系统的功能。
