Eisenberg Seth
Clin J Oncol Nurs. 2016 Aug 1;20(4):20-4AP. doi: 10.1188/16.CJON.20-04AP.
The dangers associated with handling hazardous drugs (HDs) have been well documented. Contamination of the healthcare environment, which can occur during compounding and administration, may lead to drug absorption by healthcare workers. Studies have proven that HD exposure causes numerous side effects and chromosomal aberrations.
This article examines the complex issues surrounding HD safety, including workplace culture, current guidelines, and misconceptions regarding the risks associated with exposure. Discussions include suggestions for creating a workplace culture where HD safety is an expectation, along with an update on laws and significant impending changes.
Historical data and current research are presented.
Although improvements have been made in the use of personal protective equipment, studies indicate that nurses continue to be unnecessarily at risk. Inability to fully understand the dangers, a lack of organizational safety culture, and the general inability to enforce guidelines continue to be challenging. Fortunately, a number of upcoming changes will help to build momentum for increasing nursing safety.
与处理高危药物（HDs）相关的危险已有充分记录。在配制和给药过程中可能发生的医疗环境污染，可能导致医护人员吸收药物。研究证明，接触高危药物会引起多种副作用和染色体畸变。
本文探讨了围绕高危药物安全的复杂问题，包括工作场所文化、现行指南以及对接触相关风险的误解。讨论内容包括创建一种将高危药物安全视为预期的工作场所文化的建议，以及法律更新和即将发生的重大变化。
呈现了历史数据和当前研究。
尽管在使用个人防护设备方面已有所改进，但研究表明护士仍面临不必要的风险。无法充分理解危险、缺乏组织安全文化以及普遍无法执行指南仍是挑战。幸运的是，一些即将发生的变化将有助于推动提高护理安全性。
