Nasr Deena M, Brown Robert D
Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.
Curr Cardiol Rep. 2016 Sep;18(9):86. doi: 10.1007/s11886-016-0763-4.
Unruptured intracranial aneurysms (UIA) occur in approximately 2-3 % of the population. Most of these lesions are incidentally found, asymptomatic and typically carry a benign course. Although the risk of aneurysmal subarachnoid hemorrhage is low, this complication can result in significant morbidity and mortality, making assessment of this risk the cornerstone of UIA management. This article reviews important factors to consider when managing unruptured intracranial aneurysms including patient demographics, comorbidities, family history, symptom status, and aneurysm characteristics. It also addresses screening, monitoring, medical management and current surgical and endovascular therapies.
未破裂颅内动脉瘤(UIA)在大约2%-3%的人群中出现。这些病变大多是偶然发现的,无症状,通常病程良性。虽然动脉瘤性蛛网膜下腔出血的风险较低,但这种并发症可导致严重的发病率和死亡率,因此评估这种风险是UIA管理的基石。本文综述了在管理未破裂颅内动脉瘤时需要考虑的重要因素,包括患者人口统计学、合并症、家族史、症状状态和动脉瘤特征。它还涉及筛查、监测、药物治疗以及当前的外科和血管内治疗。