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绿茶对肥胖成年人2型糖尿病危险因素的治疗潜力——综述

Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.

作者信息

Ferreira M A, Silva D M, de Morais A C, Mota J F, Botelho P B

机构信息

Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.

出版信息

Obes Rev. 2016 Dec;17(12):1316-1328. doi: 10.1111/obr.12452. Epub 2016 Jul 22.

DOI:10.1111/obr.12452
PMID:27443447
Abstract

Green tea has been associated with positive effects in the treatment of obesity and other associated comorbidities such as type 2 diabetes. These benefits are thought to be related to the anti-inflammatory and antioxidant effects of green tea and to the reduction in body fat percentage exhibited by its bioactive compounds. The predominant active compounds in green tea are flavonoid monomers known as catechins, in particular epigallocatechin-3-gallate, which is the most abundant and most effective catechin in metabolic care, particularly among obese patients. The objective of this review was to investigate the effects of green tea on body composition, oxidative stress, inflammation and insulin resistance, risk factors for the development of type 2 diabetes in obese individuals and the mechanisms that underlie the modulatory actions of green tea compounds on these risk factors. Although green tea has therapeutic potential in the treatment of obese individuals, the findings of this review demonstrate the need for a greater number of studies to confirm the positive effects of green tea, especially regarding the modulation of obesity.

摘要

绿茶已被证实对肥胖症及其他相关合并症(如2型糖尿病)的治疗具有积极作用。这些益处被认为与绿茶的抗炎和抗氧化作用以及其生物活性化合物所带来的体脂百分比降低有关。绿茶中的主要活性化合物是类黄酮单体,即儿茶素,特别是表没食子儿茶素没食子酸酯,它是代谢保健中含量最丰富、最有效的儿茶素,在肥胖患者中尤为如此。本综述的目的是研究绿茶对身体成分、氧化应激、炎症和胰岛素抵抗的影响,这些是肥胖个体发生2型糖尿病的危险因素,以及绿茶化合物对这些危险因素进行调节作用的潜在机制。尽管绿茶在肥胖个体的治疗中具有治疗潜力,但本综述的结果表明,需要更多的研究来证实绿茶的积极作用,尤其是在调节肥胖方面。

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