Kao Carol, Goldman David L
Division of Pediatric Infectious Diseases, Children's Hospital at Montefiore, The Albert Einstein College of Medicine, 111 East 210th Street, Bronx, NY, 10467, USA.
Curr Infect Dis Rep. 2016 Sep;18(9):27. doi: 10.1007/s11908-016-0534-9.
Cryptococcus neoformans is an encapsulated fungal pathogen that is remarkable for its tendency to cause meningoencephalitis, especially in patients with AIDS. While disease is less common in children than adults, it remains an important cause of morbidity and mortality among HIV-infected children without access to anti-retroviral therapy. This review highlights recent insights into both the biology and treatment of cryptococcosis with a special emphasis on the pediatric literature.
新型隐球菌是一种有荚膜的真菌病原体，以其易引发脑膜脑炎而著称，尤其是在艾滋病患者中。虽然儿童患病不如成人常见，但在无法获得抗逆转录病毒治疗的HIV感染儿童中，它仍是发病和死亡的重要原因。本综述重点介绍了近期对隐球菌病生物学和治疗方面的见解，特别着重于儿科文献。
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