[Class I and II HLA antigens in children with acute lymphoblastic leukemia].

Investigation of the distribution of HLA antigens in children with acute lymphoblastic leukemia demonstrated a significant increase of the B17 antigen frequency and a decrease of the frequency of DR7 antigen. A high index of the relative risk (RR-3.207) was also revealed for antigen B40 carriers. The typing of the children suffering from acute lymphoblastic leukemia should be carried out, as shown by the investigations, based on the immunocytological variant of acute lymphoblastic leukemia.