Reznikoff-Etievant M F, Bonneau J C, Alcalay D, Cavelier B, Touré C, Lobet R, Netter A
Unité d'Immunologie de la Reproducion, Humaine CHP/CNTS, Paris, France.
Am J Reprod Immunol. 1991 Jan;25(1):25-7. doi: 10.1111/j.1600-0897.1991.tb01059.x.
Previously, several groups reported an increase in HLA antigen-sharing in couples suffering from unexplained repeated spontaneous abortions. It was felt necessary to find out if HLA sharing could have any effect on children born after a successful pregnancy. The birthweight figures of children of 76 couples with repeated spontaneous abortions were analyzed. The results show a significantly lower birthweight in babies born from those couples, presenting a high incidence of HLA antigen-sharing, particularly concerning class II antigens.
