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中枢神经系统淋巴瘤的神经影像学

Neuroimaging in Central Nervous System Lymphoma.

作者信息

Nabavizadeh Seyed Ali, Vossough Arastoo, Hajmomenian Mehrdad, Assadsangabi Reza, Mohan Suyash

机构信息

Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19014, USA.

Department of Radiology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

出版信息

Hematol Oncol Clin North Am. 2016 Aug;30(4):799-821. doi: 10.1016/j.hoc.2016.03.005.

Abstract

Primary central nervous system lymphoma (PCNSL) is a rare aggressive high-grade type of extranodal lymphoma. PCNSL can have a variable imaging appearance and can mimic other brain disorders such as encephalitis, demyelination, and stroke. In addition to PCNSL, the CNS can be secondarily involved by systemic lymphoma. Computed tomography and conventional MRI are the initial imaging modalities to evaluate these lesions. Recently, however, advanced MRI techniques are more often used in an effort to narrow the differential diagnosis and potentially inform diagnostic and therapeutic decisions.

摘要

原发性中枢神经系统淋巴瘤(PCNSL)是一种罕见的侵袭性高级别结外淋巴瘤。PCNSL的影像学表现可能多种多样,可模仿其他脑部疾病,如脑炎、脱髓鞘疾病和中风。除PCNSL外,中枢神经系统也可能继发于全身性淋巴瘤。计算机断层扫描和传统磁共振成像(MRI)是评估这些病变的初始影像学检查方法。然而,近来先进的MRI技术更常被用于努力缩小鉴别诊断范围,并可能为诊断和治疗决策提供依据。

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