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高毒力副猪嗜血杆菌11型菌株SC1401的全基因组序列

Complete Genome Sequence of Highly Virulent Haemophilus parasuis Serotype 11 Strain SC1401.

作者信息

Dai Ke, Jin Jin, Wen Yiping, Wen Xintian, He Lvqin, Cao Sanjie, Huang Xiaobo, Wu Rui, Zhao Qin

机构信息

Research Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China.

Research Center of Swine Disease, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China

出版信息

Genome Announc. 2016 Jul 21;4(4):e00628-16. doi: 10.1128/genomeA.00628-16.

Abstract

Haemophilus parasuis, a normal Gram-negative bacterium, may cause Glässer's disease and pneumonia in pigs. This study aims to identify the genes related to natural competence of the serotype 11 strain SC1401, which frequently shows competence and high pathogenicity. SC1401 shows many differences from strains without natural competence within the molecular basis. We performed complete genome sequencing together with restriction modification system analysis to lay the foundation for later study.

摘要

副猪嗜血杆菌是一种常见的革兰氏阴性菌,可导致猪的格拉泽氏病和肺炎。本研究旨在鉴定与11型菌株SC1401自然感受态相关的基因,该菌株经常表现出感受态和高致病性。SC1401在分子基础上与无自然感受态的菌株有许多差异。我们进行了全基因组测序以及限制修饰系统分析,为后续研究奠定基础。

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