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来自印度的一株自然重配传染性法氏囊病病毒的全基因组序列分析

Complete Genome Sequence Analysis of a Naturally Reassorted Infectious Bursal Disease Virus from India.

作者信息

Raja P, Senthilkumar T M A, Parthiban M, Thangavelu A, Gowri A Mangala, Palanisammi A, Kumanan K

机构信息

Department of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India.

Department of Animal Biotechnology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai, India

出版信息

Genome Announc. 2016 Jul 21;4(4):e00709-16. doi: 10.1128/genomeA.00709-16.

Abstract

The novel infectious bursal disease virus (IBDV) isolate BGE14/ABT1/MVC/India is a very virulent IBDV that was isolated from broiler flocks in southern parts of India during 2014. Here, we report, for the first time in India, the complete genome sequence of BGE14/ABT1/MVC/India, a reassortment strain with segments A and B derived from a very virulent IBDV strain and an attenuated IBDV, respectively. The findings from this study provide additional insight into the genetic exchange between attenuated and very virulent strains of IBDV circulating in the field.

摘要

新型传染性法氏囊病病毒(IBDV)分离株BGE14/ABT1/MVC/印度是一种超强毒IBDV,于2014年从印度南部的肉鸡群中分离得到。在此,我们首次在印度报道了BGE14/ABT1/MVC/印度的全基因组序列,这是一种重配毒株,其A和B片段分别来源于一种超强毒IBDV毒株和一种弱毒IBDV。本研究结果为深入了解田间流行的IBDV弱毒株和超强毒株之间的基因交换提供了更多信息。

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