Mukherjee Piyali, Roy Pranab
Laboratory of Molecular Biology, Department of Biotechnology, Burdwan University Burdwan, India.
Department of Biotechnology, Haldia Institute of Technology Haldia, India.
Front Microbiol. 2016 Jun 22;7:967. doi: 10.3389/fmicb.2016.00967. eCollection 2016.
The gram negative bacterium Stenotrophomonas is rapidly evolving as a nosocomial pathogen in immuno-compromised patients. Treatment of Stenotrophomonas maltophilia infections is problematic because of their increasing resistance to multiple antibiotics. This article aims to review the multi-disciplinary role of Stenotrophomonas in our environment with special focus on their metabolic and genetic potential in relation to bioremediation and phytoremediation. Current and emerging treatments and diagnosis for patients infected with S. maltophilia are discussed besides their capability of production of novel bioactive compounds. The plant growth promoting characteristics of this bacterium has been considered with special reference to secondary metabolite production. Nano-particle synthesis by Stenotrophomonas has also been reviewed in addition to their applications as effective biocontrol agents in plant and animal pathogenesis.
革兰氏阴性细菌嗜麦芽窄食单胞菌正迅速演变为免疫功能低下患者医院感染的病原菌。嗜麦芽窄食单胞菌感染的治疗存在问题，因为它们对多种抗生素的耐药性不断增加。本文旨在综述嗜麦芽窄食单胞菌在我们环境中的多学科作用，特别关注其与生物修复和植物修复相关的代谢和遗传潜力。除了讨论嗜麦芽窄食单胞菌产生新型生物活性化合物的能力外，还讨论了目前和新出现的针对嗜麦芽窄食单胞菌感染患者的治疗方法和诊断方法。特别参考了该细菌产生次生代谢产物的情况，考虑了其促进植物生长的特性。除了嗜麦芽窄食单胞菌作为动植物发病机制中有效的生物防治剂的应用外，还综述了其纳米颗粒合成情况。
