前列腺癌转移至左拇趾远节指骨：首例确诊病例及文献综述
Prostate cancer metastasis to the distal phalanx of the left hallux: The first confirmed case and literature review.
作者信息
Sui Xinbing, Hu Yan, Zhang Cheng, Pan Hongming, Li Da
机构信息
Department of Medical Oncology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
Department of Pathology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang 310016, P.R. China.
出版信息
Oncol Lett. 2016 Aug;12(2):1074-1078. doi: 10.3892/ol.2016.4701. Epub 2016 Jun 13.
Prostate cancer is one of the most common carcinomas in Asia, as well as all over the world. The vast majority of prostate cancer patients present with bone metastases, which mainly involve the axial bones, with pain as the most common symptom. The present study reports the first case of prostate cancer metastasis to the hallux in a 73-year-old man who presented with pain and a swollen phalanx of the left hallux. This symptom developed gradually over a period of several months and could not be improved with the common treatments. Due to a pathological fracture, amputation of the left phalanx was performed. Notably, the immunohistochemical examinations of the surgical sample demonstrated the presence of a metastatic lesion from prostate cancer. The present study describes an unusual presentation involving phalangeal metastasis in a prostate cancer patient, and a systematic review of reported cases of rare metastatic events in prostate cancer is also discussed.
前列腺癌是亚洲以及全球最常见的癌症之一。绝大多数前列腺癌患者会出现骨转移，主要累及中轴骨，疼痛是最常见的症状。本研究报告了首例前列腺癌转移至拇趾的病例，患者为一名73岁男性，表现为左拇趾疼痛和趾骨肿胀。这种症状在几个月的时间里逐渐发展，常规治疗无法改善。由于病理性骨折，对左趾骨进行了截肢。值得注意的是，手术样本的免疫组化检查显示存在前列腺癌转移灶。本研究描述了一例前列腺癌患者罕见的趾骨转移表现，并对已报道的前列腺癌罕见转移事件病例进行了系统综述。
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