Kim Woong-Beom, Hyun Seung-Jae, Choi Hoyong, Kim Ki-Jeong, Jahng Tae-Ahn, Kim Hyun-Jib
Department of Neurosurgery, Spine Center, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
J Korean Neurosurg Soc. 2016 Jul;59(4):385-91. doi: 10.3340/jkns.2016.59.4.385. Epub 2016 Jul 8.
The purpose of this study was to evaluate long-term follow-up radiologic/clinical outcomes of patients who underwent anterior cervical discectomy and inter-body fusion (ACDF) with stand-alone cages (SAC) in a single academic institution.
Total 99 patients who underwent ACDF with SAC between February 2004 and December 2012 were evaluated retrospectively. A total of 131 segments were enrolled in this study. Basic demographic information, radiographic [segmental subsidence rate, fusion rate, C2-7 global angle, and segmental angle changes)/clinical outcomes (by Odom's criteria and visual analog score (VAS)] and complications were evaluated to determine the long-term outcomes.
The majority were males (55 vs. 44) with average age of 53.2. Mean follow-up period was 62.9 months. The segmental subsidence rate was 53.4% and fusion rate was 73.3%. In the subsidence group, anterior intervertebral height (AIH) had more tendency of subsiding than middle or posterior intervertebral height (p=0.01). The segmental angle led kyphotic change related to the subsidence of the AIH. Adjacent segmental disease was occurred in 18 (18.2%) patients. Total 6 (6%) reoperations were performed at the index level. There was no statistical significance between clinical and radiological outcomes. But, overall long-term clinical outcome by Odom's criteria was unsatisfactory (64.64%). The neck and arm VAS score were increased by over time.
Long-term outcomes of ACDF with SAC group were acceptable but not satisfactory. For optimal decision making, more additional comparative long-term outcome data is needed between ACDF with SAC and ACDF with plating.
本研究旨在评估在单一学术机构中接受前路颈椎间盘切除及椎间融合术(ACDF)并使用独立椎间融合器(SAC)的患者的长期影像学/临床结局。
回顾性评估2004年2月至2012年12月间99例行ACDF并使用SAC的患者。本研究共纳入131个节段。评估基本人口统计学信息、影像学指标(节段沉降率、融合率、C2 - 7整体角度及节段角度变化)/临床结局(依据奥多姆标准和视觉模拟评分(VAS))以及并发症,以确定长期结局。
大多数为男性(55例对44例),平均年龄53.2岁。平均随访期为62.9个月。节段沉降率为53.4%,融合率为73.3%。在沉降组中,椎体前缘高度(AIH)比椎体中部或后部高度更易发生沉降(p = 0.01)。节段角度因AIH沉降导致后凸改变。18例(18.2%)患者发生相邻节段病变。共6例(6%)在初次手术节段进行了再次手术。临床和影像学结局之间无统计学意义。但是,依据奥多姆标准的总体长期临床结局并不理想(64.64%)。颈部和手臂VAS评分随时间增加。
ACDF联合SAC组的长期结局尚可但并不令人满意。为了做出最佳决策,需要更多ACDF联合SAC与ACDF联合钢板固定的长期对比结局数据。