Durand Wesley M, Khanna Rajan, Nazario-Ferrer Gabriel I, Lee Sang H, Skolasky Richard L, Jain Amit
Department of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Global Spine J. 2025 May;15(4):2014-2019. doi: 10.1177/21925682241279528. Epub 2024 Aug 27.
Study Designretrospective study.ObjectiveTo investigate the incidence of all-cause revision surgery between plated vs stand-alone cage constructs for single level ACDF.MethodsWe retrospectively analyzed a commercial insurance claims database. Patients 18-65 years-old were included if they underwent single-level inpatient ACDF (defined with CPT codes) from 2010 - 2018, with a minimum of 2-year continuous insurance enrollment. The primary independent variable was the use of anterior plating vs zero profile device or stand-alone cage. Synthetic (ie, metal, PEEK, etc.) vs allograft interbody was a secondary independent variable. The primary outcome variable was revision cervical arthrodesis after the index operation.ResultsIn total, 21092 patients undergoing single-level inpatient ACDF were included. 10.0% received a stand-alone cage during the index operation. Mean follow-up duration was 4.5 years. Revision arthrodesis occurred in 8.2% of patients overall, at a mean of 2.4 years after the index surgery. Patients with anterior plating had a lower rate of all-cause revision surgery in unadjusted (overall rate 8.1% vs 9.6%, = 0.0185) and adjusted analysis (OR 0.78, = 0.0016) vs stand-alone cages. Patients with stand-alone cages had higher rates of revision with a posterior approach than did patients with plated constructs. In sub-analysis, the combination of a stand-alone interbody device with an allograft had significantly higher odds of revision than other combinations of devices.ConclusionAmong commercially insured patients ≤65 years-old undergoing single-level ACDF, anterior plating was associated with a reduced incidence of revision surgery compared to stand-alone cages within the follow up period of our study.
回顾性研究。
探讨单节段ACDF手术中钢板固定与单独椎间融合器植入两种方式下全因翻修手术的发生率。
我们回顾性分析了一个商业保险理赔数据库。纳入年龄在18 - 65岁之间,于2010年至2018年接受单节段住院ACDF手术(根据CPT编码定义)且至少连续参保2年的患者。主要自变量是使用前路钢板与零切迹装置或单独椎间融合器。异体骨与人工合成(如金属、聚醚醚酮等)椎间融合器作为次要自变量。主要结局变量是初次手术后的颈椎翻修融合术。
总共纳入了21092例行单节段住院ACDF手术的患者。10.0%的患者在初次手术中接受了单独椎间融合器植入。平均随访时间为4.5年。总体上,8.2%的患者发生了翻修融合术,平均在初次手术后2.4年。在未调整分析(总体发生率8.1%对9.6%,P = 0.0185)和调整分析(OR 0.78,P = 0.0016)中,前路钢板固定的患者全因翻修手术发生率低于单独椎间融合器植入的患者。与钢板固定结构的患者相比,单独椎间融合器植入的患者后路翻修率更高。在亚组分析中,单独椎间融合器与异体骨联合使用时的翻修几率显著高于其他器械组合。
在65岁及以下接受商业保险的单节段ACDF手术患者中,在我们的研究随访期内,与单独椎间融合器相比,前路钢板固定与翻修手术发生率降低相关。