Kim Jae-Min, Kim Min-Wook, Do Hyun-Jung
Department of Rehabilitation, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Ann Rehabil Med. 2016 Jun;40(3):463-9. doi: 10.5535/arm.2016.40.3.463. Epub 2016 Jun 29.
To investigate the influence of hyperlipidemia on the treatment of supraspinatus tendinopathy, with or without tear.
We retrospectively reviewed the data of patients with shoulder pain and patients with supraspinatus tendinopathy, with or without tear, were included in the study. Exclusion criteria were prior shoulder surgery, prior steroid injection, neurological diseases that could lead to shoulder pain, and use of lipid-lowering medication. According to the serum lipid profiles, patients were assigned to either the hyperlipidemia or non-hyperlipidemia group. By analyzing the numeric rating scale (NRS) before treatment, and at 2 weeks and 8 weeks after treatment, we compared the difference in treatment effect between the two groups.
No significant baseline difference was found among the two groups for age, gender, body mass index, duration of pain, side of pain, range of motion of affected shoulder, or physical examination. On the repeated-measures analysis of variance, NRS scores significantly decreased with time for both groups (p<0.001). When analyzing the effect of time between the subjects factor, there was significant difference in the treatment effect between the two groups (p<0.001), namely NRS was less decreased in the hyperlipidemia group.
We found that hyperlipidemia may be an adversely affecting factor in the treatment of supraspinatus tendinopathy with or without tear.
研究高脂血症对伴或不伴撕裂的冈上肌腱病治疗效果的影响。
我们回顾性分析了肩部疼痛患者以及伴或不伴撕裂的冈上肌腱病患者的数据。纳入标准为肩部疼痛患者。排除标准为既往肩部手术史、既往类固醇注射史、可导致肩部疼痛的神经疾病以及使用降脂药物。根据血脂水平，将患者分为高脂血症组和非高脂血症组。通过分析治疗前、治疗后2周和8周的数字评定量表（NRS），比较两组治疗效果的差异。
两组在年龄、性别、体重指数、疼痛持续时间、疼痛部位、患侧肩部活动范围或体格检查方面，基线无显著差异。重复测量方差分析显示，两组的NRS评分均随时间显著降低（p<0.001）。分析组间因素的时间效应时，两组治疗效果存在显著差异（p<0.001），即高脂血症组NRS评分降低较少。
我们发现高脂血症可能是影响伴或不伴撕裂的冈上肌腱病治疗效果的不利因素。
