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暗色丝孢霉病

Phaeohyphomycosis.

作者信息

Kumar K Kiran, Hallikeri Kaveri

机构信息

Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences, Sattur, Dharwad, India.

出版信息

Indian J Pathol Microbiol. 2008 Oct-Dec;51(4):556-8. doi: 10.4103/0377-4929.43761.

Abstract

Phaeohyphomycosis, caused by heterogeneous group of phaeoid fungi causes both subcutaneous and systemic infections. The disease is more of a histopathological than a clinical entity. We present a case of phaeohyphomycosis in a 29-year-old male who presented with the complaint of painful swelling of the right eye of 1-year duration. Computed tomography (CT) scan showed an abnormal hyper dense enhancing soft tissue in the extra coronal aspect of the right orbit along the superolateral and superomedial aspect. A provisional clinical diagnosis of lymphoma or fungal infection was entertained. Histopathology revealed granulomas with numerous multinucleated giant cells and fungal hyphae within and in between the giant cells. Per-iodic acid Schiff (PAS stain) was used to confirm the presence of hyphae. Based on the clinical, CT and histopathological features, a diagnosis of Phaeohyphomycosis was given.

摘要

暗色丝孢霉病由一组异质性的暗色真菌引起,可导致皮下和全身感染。该疾病更多是一种组织病理学上的实体,而非临床实体。我们报告一例29岁男性的暗色丝孢霉病病例,该患者主诉右眼疼痛性肿胀持续1年。计算机断层扫描(CT)显示右眼眶冠状面外侧和内侧上方有异常高密度强化软组织。初步临床诊断考虑淋巴瘤或真菌感染。组织病理学显示肉芽肿内有大量多核巨细胞,巨细胞内外可见真菌菌丝。采用过碘酸希夫染色(PAS染色)来确认菌丝的存在。根据临床、CT和组织病理学特征,诊断为暗色丝孢霉病。

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