Kumar K Kiran, Hallikeri Kaveri
Department of Oral and Maxillofacial Pathology, SDM College of Dental Sciences, Sattur, Dharwad, India.
Indian J Pathol Microbiol. 2008 Oct-Dec;51(4):556-8. doi: 10.4103/0377-4929.43761.
Phaeohyphomycosis, caused by heterogeneous group of phaeoid fungi causes both subcutaneous and systemic infections. The disease is more of a histopathological than a clinical entity. We present a case of phaeohyphomycosis in a 29-year-old male who presented with the complaint of painful swelling of the right eye of 1-year duration. Computed tomography (CT) scan showed an abnormal hyper dense enhancing soft tissue in the extra coronal aspect of the right orbit along the superolateral and superomedial aspect. A provisional clinical diagnosis of lymphoma or fungal infection was entertained. Histopathology revealed granulomas with numerous multinucleated giant cells and fungal hyphae within and in between the giant cells. Per-iodic acid Schiff (PAS stain) was used to confirm the presence of hyphae. Based on the clinical, CT and histopathological features, a diagnosis of Phaeohyphomycosis was given.
暗色丝孢霉病由一组异质性的暗色真菌引起，可导致皮下和全身感染。该疾病更多是一种组织病理学上的实体，而非临床实体。我们报告一例29岁男性的暗色丝孢霉病病例，该患者主诉右眼疼痛性肿胀持续1年。计算机断层扫描（CT）显示右眼眶冠状面外侧和内侧上方有异常高密度强化软组织。初步临床诊断考虑淋巴瘤或真菌感染。组织病理学显示肉芽肿内有大量多核巨细胞，巨细胞内外可见真菌菌丝。采用过碘酸希夫染色（PAS染色）来确认菌丝的存在。根据临床、CT和组织病理学特征，诊断为暗色丝孢霉病。
