Dharmarajan Kumar, Strait Kelly M, Tinetti Mary E, Lagu Tara, Lindenauer Peter K, Lynn Joanne, Krukas Michelle R, Ernst Frank R, Li Shu-Xia, Krumholz Harlan M
Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, Connecticut.
J Am Geriatr Soc. 2016 Aug;64(8):1574-82. doi: 10.1111/jgs.14303. Epub 2016 Jul 22.
To determine how often hospitalized older adults principally diagnosed with pneumonia, chronic obstructive pulmonary disease (COPD), or heart failure (HF) are concurrently treated for two or more of these acute cardiopulmonary conditions.
Retrospective cohort study.
368 U.S. hospitals in the Premier research database.
Individuals aged 65 and older principally hospitalized with pneumonia, COPD, or HF in 2009 or 2010.
Proportion of diagnosed episodes of pneumonia, COPD, or HF concurrently treated for two or more of these acute cardiopulmonary conditions during the first 2 hospital days.
Of 91,709 diagnosed pneumonia hospitalizations, 32% received treatment for two or more acute cardiopulmonary conditions (18% for HF, 18% for COPD, 4% for both). Of 41,052 diagnosed COPD hospitalizations, 19% received treatment for two or more acute cardiopulmonary conditions (all of which involved additional HF treatment). Of 118,061 diagnosed HF hospitalizations, 38% received treatment for two or more acute cardiopulmonary conditions (34% for pneumonia, 9% for COPD, 5% for both).
Hospitalized older adults diagnosed with pneumonia, COPD, or HF are frequently treated for two or more acute cardiopulmonary conditions, suggesting that clinical syndromes often fall between traditional diagnostic categories. Research is needed to evaluate the risks and benefits of real-world treatment for the many older adults whose presentations elicit diagnostic uncertainty or concern about coexisting acute conditions.
确定主要诊断为肺炎、慢性阻塞性肺疾病(COPD)或心力衰竭(HF)的住院老年人同时接受两种或更多种这些急性心肺疾病治疗的频率。
回顾性队列研究。
Premier研究数据库中的368家美国医院。
2009年或2010年主要因肺炎、COPD或HF住院的65岁及以上个体。
在住院的头2天内,肺炎、COPD或HF诊断发作同时接受两种或更多种这些急性心肺疾病治疗的比例。
在91,709例诊断为肺炎的住院病例中,32%接受了两种或更多种急性心肺疾病的治疗(18%为HF,18%为COPD,4%为两者兼有)。在41,052例诊断为COPD的住院病例中,19%接受了两种或更多种急性心肺疾病的治疗(所有这些都涉及额外的HF治疗)。在118,061例诊断为HF的住院病例中,38%接受了两种或更多种急性心肺疾病的治疗(34%为肺炎,9%为COPD,5%为两者兼有)。
诊断为肺炎、COPD或HF的住院老年人经常接受两种或更多种急性心肺疾病的治疗,这表明临床综合征往往介于传统诊断类别之间。对于许多临床表现引发诊断不确定性或对并存急性疾病担忧的老年人,需要开展研究来评估实际治疗的风险和益处。