Division of Internal Medicine University of Michigan Ann Arbor MI.
Institute of Healthcare Policy and Innovation, University of Michigan Ann Arbor MI.
J Am Heart Assoc. 2022 Dec 6;11(23):e025730. doi: 10.1161/JAHA.122.025730. Epub 2022 Nov 16.
Background Descriptions of do not attempt resuscitation (DNAR) orders in heart failure (HF) are limited. We describe use of DNAR orders in HF hospitalizations relative to other common conditions, focusing on race. Methods and Results This was a retrospective study of all adult hospitalizations for HF, acute myocardial infarction (AMI), chronic obstructive pulmonary disease (COPD), and pneumonia from 2010 to 2016 using the California State Inpatient Dataset. Using a hierarchical multivariable logistic regression model with random effects for the hospital, we identified factors associated with DNAR orders for each condition. For racial variation, hospitals were divided into quintiles based on proportion of Black patients cared for. Our cohort comprised 399 816 HF, 190 802 AMI, 192 640 COPD, and 269 262 pneumonia hospitalizations. DNAR orders were most prevalent in HF (11.9%), followed by pneumonia (11.1%), COPD (7.9%), and AMI (7.1%). Prevalence of DNAR orders did not change from 2010 to 2016 for each condition. For all conditions, DNAR orders were more common in elderly people, women, and White people with significant site-level variation across 472 hospitals. For HF and COPD, hospitalizations at sites that cared for a higher proportion of Black patients were less likely associated with DNAR orders. For AMI and pneumonia, conditions such as dementia and malignancy were strongly associated with DNAR orders. Conclusions DNAR orders were present in 12% of HF hospitalizations, similar to pneumonia but higher than AMI and COPD. For HF, we noted significant variability across sites when stratified by proportion of Black patients cared for, suggesting geographic and racial differences in end-of-life care.
背景描述在心力衰竭(HF)中不尝试复苏(DNAR)的医嘱是有限的。我们描述了 HF 住院患者相对于其他常见疾病(重点是种族)使用 DNAR 医嘱的情况。
方法和结果这是一项使用加利福尼亚州住院患者数据集,回顾性研究 2010 年至 2016 年所有成人 HF、急性心肌梗死(AMI)、慢性阻塞性肺疾病(COPD)和肺炎住院患者的研究。使用具有医院随机效应的分层多变量逻辑回归模型,我们确定了与每种疾病的 DNAR 医嘱相关的因素。对于种族差异,根据所治疗的黑人患者比例将医院分为五组。我们的队列包括 399816 例 HF、190802 例 AMI、192640 例 COPD 和 269262 例肺炎住院患者。DNAR 医嘱在 HF 中最为常见(11.9%),其次是肺炎(11.1%)、COPD(7.9%)和 AMI(7.1%)。每种疾病的 DNAR 医嘱的比例从 2010 年到 2016 年都没有变化。对于所有疾病,DNAR 医嘱在老年人、女性和白人中更为常见,在 472 家医院中存在显著的地点水平差异。对于 HF 和 COPD,在黑人患者比例较高的医院就诊的患者,DNAR 医嘱的可能性较小。对于 AMI 和肺炎,痴呆和恶性肿瘤等疾病与 DNAR 医嘱密切相关。
结论 DNAR 医嘱在 HF 住院患者中占 12%,与肺炎相似,但高于 AMI 和 COPD。对于 HF,我们注意到按所治疗的黑人患者比例分层时,不同地点之间存在显著差异,表明临终关怀存在地理和种族差异。