IL-17 Responses Are the Dominant Inflammatory Signal Linking Inverse, Erythrodermic, and Chronic Plaque Psoriasis.
作者信息
Xing Xianying, Liang Yun, Sarkar Mrinal K, Wolterink Liza, Swindell William R, Voorhees John J, Harms Paul W, Kahlenberg Joanne M, Johnston Andrew, Gudjonsson Johann E
机构信息
Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Department of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
出版信息
J Invest Dermatol. 2016 Dec;136(12):2498-2501. doi: 10.1016/j.jid.2016.07.008. Epub 2016 Jul 21.
Abstract
摘要
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本文引用的文献
1
IκBζ is a key driver in the development of psoriasis.IκBζ是银屑病发病过程中的关键驱动因素。
Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5825-33. doi: 10.1073/pnas.1509971112. Epub 2015 Oct 12.
2
T(H)17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26.辅助性T细胞17通过白细胞介素26促进微生物杀伤和对DNA的天然免疫感知。
Nat Immunol. 2015 Sep;16(9):970-9. doi: 10.1038/ni.3211. Epub 2015 Jul 13.
3
Psoriasis inversa: A separate identity or a variant of psoriasis vulgaris?反向性银屑病：是一种独立的疾病还是寻常型银屑病的一种变异型？
Clin Dermatol. 2015 Jul-Aug;33(4):456-61. doi: 10.1016/j.clindermatol.2015.04.007. Epub 2015 Apr 8.
4
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.强化荟萃分析和重复研究确定了五个新的银屑病易感基因座。
Nat Commun. 2015 May 5;6:7001. doi: 10.1038/ncomms8001.
5
Efficacy and safety of open-label ixekizumab treatment in Japanese patients with moderate-to-severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis.在中重度斑块状银屑病、红皮病型银屑病和泛发性脓疱型银屑病日本患者中，开放性 ixekizumab 治疗的疗效和安全性。
J Eur Acad Dermatol Venereol. 2015 Jun;29(6):1148-55. doi: 10.1111/jdv.12773. Epub 2014 Oct 30.
6
Modulation of epidermal transcription circuits in psoriasis: new links between inflammation and hyperproliferation.银屑病表皮转录电路的调节：炎症与过度增殖之间的新联系。
PLoS One. 2013 Nov 15;8(11):e79253. doi: 10.1371/journal.pone.0079253. eCollection 2013.
7
Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients.剖析银屑病转录组：来自 163 位患者病变组织的炎症和细胞因子驱动基因表达。
BMC Genomics. 2013 Aug 1;14:527. doi: 10.1186/1471-2164-14-527.
8
Treatment of erythrodermic psoriasis: from the medical board of the National Psoriasis Foundation.红皮病型银屑病的治疗：来自全国银屑病基金会医学委员会。
J Am Acad Dermatol. 2010 Apr;62(4):655-62. doi: 10.1016/j.jaad.2009.05.048. Epub 2009 Aug 8.
9
Pustular and erythrodermic psoriasis.
Dermatol Clin. 1995 Oct;13(4):757-70.
10
Infectious complications of erythrodermic psoriasis.红皮病型银屑病的感染性并发症。
J Am Acad Dermatol. 1996 May;34(5 Pt 2):911-4. doi: 10.1016/s0190-9622(96)90078-x.
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