Sidaly Rivan, Schmalfuss Andreas, Skaare Anne B, Sehic Amer, Stiris Tom, Espelid Ivar
Department of Biomaterials, Institute of Clinical Dentistry, Faculty of Dentistry, University of Oslo, Oslo, Norway.
Department of Biomaterials, Faculty of Dentistry, PO Box 1109, Blindern, N-0317, Oslo, Norway.
BMC Oral Health. 2016 Jul 22;17(1):25. doi: 10.1186/s12903-016-0253-5.
The aetiology of molar incisor hypomineralisation (MIH) is unclear. The asymmetric distribution of MIH in the dentition may indicate that an insult of short duration that affects ameloblasts at a vulnerable stage could be a causative factor. Apgar ≤ 5 at 5 min may indicate asphyxia (hypoxic-ischemic insult) during birth. It was hypnotised that low Apgar score during birth may cause MIH. The present study aimed to examine a possible association between Apgar ≤ 5 at 5 min and the occurrence of MIH.
Two study groups were selected for examination. The cases comprised 67 children aged 8-10 years born with Apgar score equal to or below 5 after 5 min. The control group comprised 157 age-matched healthy children. First permanent molars, second primary molars and all permanent incisors were examined in all children. Clinical examination was undertaken by two calibrated examiners and intraoral close-up photographs of the teeth were later evaluated by three calibrated and blinded clinicians. Demarcated opacities, post-eruptive breakdown, atypical restorations and extractions due to MIH, according to the criteria of the European Association of Paediatric Dentistry, were assessed.
The prevalence of MIH did not differ between the two groups. A chi-square test failed to confirm any statistically significant relationship between 5-min Apgar scores and MIH occurrence. In addition, there was no statistically significant relationship between the number of affected first permanent molars in cases and controls.
There was no association between Apgar ≤ 5 at 5 min and the occurrence of MIH.
磨牙釉质矿化不全（MIH）的病因尚不清楚。MIH在牙列中的不对称分布可能表明，在脆弱阶段影响成釉细胞的短期损伤可能是一个致病因素。出生时5分钟阿氏评分≤5可能表明出生时窒息（缺氧缺血性损伤）。有人推测出生时阿氏评分低可能导致MIH。本研究旨在探讨出生时5分钟阿氏评分≤5与MIH发生之间的可能关联。
选择两个研究组进行检查。病例组包括67名8至10岁的儿童，他们出生时5分钟阿氏评分等于或低于5分。对照组包括157名年龄匹配的健康儿童。对所有儿童的第一恒磨牙、第二乳磨牙和所有恒切牙进行检查。由两名经过校准的检查者进行临床检查，随后由三名经过校准且不知情的临床医生对牙齿的口腔内特写照片进行评估。根据欧洲儿童牙科学会的标准，评估因MIH导致的界限性釉质混浊、萌出后崩解、非典型修复体和拔牙情况。
两组之间MIH的患病率没有差异。卡方检验未能证实5分钟阿氏评分与MIH发生之间存在任何统计学上的显著关系。此外，病例组和对照组中受影响的第一恒磨牙数量之间也没有统计学上的显著关系。
出生时5分钟阿氏评分≤5与MIH的发生之间没有关联。
