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Neurotrophic action of bombesin on ventral spinal cord in culture.

作者信息

Iwasaki Y, Kinoshita M, Ikeda K

机构信息

Fourth Department of Internal Medicine, Toho University, Ohashi Hospital, Tokyo, Japan.

出版信息

Int J Neurosci. 1989 Apr;45(3-4):195-8. doi: 10.3109/00207458908986231.

DOI:10.3109/00207458908986231
PMID:2744959
Abstract

Studies with orgonotypic culture of ventral spinal cord revealed that bombesin at 10(-4) to 10(-12) M exerts a marked growth-stimulating effect. The presence of bombesin, the neuritic extension of ventral spinal cord exceeds control values 1.5-4.8 times. The growth zone of spinal cord explants increases in the bombesin treated cultures. The possible mechanism of trophic effect of bombesin on ventral cord was briefly discussed.

摘要

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